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Chembiochem : a European Journal of Chemical Biology|April 30, 2014
Charge density influences C1 domain ligand affinity and membrane interactionsJessica S Kelsey, Tamas Geczy, Nancy E Lewin, et al.Organic Letters|December 31, 2008
Substitution on the A-ring confers to bryopyran analogues the unique biological activity characteristic of bryostatins and distinct from that of the phorbol estersGary E Keck, Yam B Poudel, Dennie S Welch, et al.Journal of Medicinal Chemistry|March 19, 2004
Antineoplastic agents. 499. Synthesis of hystatin 2 and related 1H-benzo[de][1,6]-naphthyridinium salts from aaptamineGeorge R Pettit, Holger Hoffmann, Delbert L Herald, et al.Journal of Medicinal Chemistry|April 22, 2009
Conformationally constrained analogues of diacylglycerol (DAG). 31. Modulation of the biological properties of diacylgycerol lactones (DAG-lactones) containing rigid-rod acyl groups separated from the core lactone by spacer units of different lengthsMaria J Comin, Gabriella Czifra, Noemi Kedei, et al.Bioorganic & Medicinal Chemistry|April 11, 2017
Exploring the influence of indololactone structure on selectivity for binding to the C1 domains of PKCα, PKCε, and RasGRPEleonora Elhalem, Lucía Gandolfi Donadío, Xiaoling Zhou, et al.Chembiochem : a European Journal of Chemical Biology|May 5, 2011
Some phorbol esters might partially resemble bryostatin 1 in their actions on LNCaP prostate cancer cells and U937 leukemia cellsNoemi Kedei, Emanuel Lubart, Nancy E Lewin, et al.The Journal of Biological Chemistry|March 30, 2016
Structural Basis for the Failure of the C1 Domain of Ras Guanine Nucleotide Releasing Protein 2 (RasGRP2) to Bind Phorbol Ester with High AffinityAgnes Czikora, Daniel J Lundberg, Adelle Abramovitz, et al.Plos One|August 31, 2013
RasGRPs are targets of the anti-cancer agent ingenol-3-angelateXiaohua Song, Ana Lopez-Campistrous, Lucy Sun, et al.The Journal of Organic Chemistry|March 31, 2004
Antineoplastic agents 491. Synthetic conversion of aaptamine to isoaaptamine, 9-demethylaaptamine, and 4-methylaaptamineGeorge R Pettit, Holger Hoffmann, Delbert L Herald, et al.The Journal of Biological Chemistry|June 1, 2005
A novel diacylglycerol-lactone shows marked selectivity in vitro among C1 domains of protein kinase C (PKC) isoforms alpha and delta as well as selectivity for RasGRP compared with PKCalphaYongmei Pu, Nicholas A Perry, Dazhi Yang, et al.Pageof 7