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Bioorganic & Medicinal Chemistry Letters|April 21, 2015
Synthetic studies of five-membered heteroaromatic derivatives as potassium-competitive acid blockers (P-CABs)Yasuyoshi Arikawa, Atsushi Hasuoka, Haruyuki Nishida, et al.
Bioorganic & Medicinal Chemistry|October 11, 2016
Novel approach of fragment-based lead discovery applied to renin inhibitorsMichiko Tawada, Shinkichi Suzuki, Yasuhiro Imaeda, et al.
Bioorganic & Medicinal Chemistry Letters|September 15, 2012
Serum stability of selected decapeptide agonists of KISS1R using pseudopeptidesTaiji Asami, Naoki Nishizawa, Yoshihiro Ishibashi, et al.
Bioorganic & Medicinal Chemistry|October 1, 2016
Structure-based design of a new series of N-(piperidin-3-yl)pyrimidine-5-carboxamides as renin inhibitorsYasuhiro Imaeda, Michiko Tawada, Shinkichi Suzuki, et al.
Bioorganic & Medicinal Chemistry|May 15, 2012
Discovery, synthesis, and biological evaluation of novel pyrrole derivatives as highly selective potassium-competitive acid blockersHaruyuki Nishida, Atsushi Hasuoka, Yasuyoshi Arikawa, et al.
Journal of Medicinal Chemistry|September 20, 2013
Design, synthesis, and biological evaluation of novel investigational nonapeptide KISS1R agonists with testosterone-suppressive activityTaiji Asami, Naoki Nishizawa, Hisanori Matsui, et al.
Bioorganic & Medicinal Chemistry|May 20, 2017
Discovery, synthesis, and structure-activity relations of 3,4-dihydro-1H-spiro(naphthalene-2,2'-piperidin)-1-ones as potassium-competitive acid blockersToshihiro Imaeda, Koji Ono, Kazuo Nakai, et al.
Bioorganic & Medicinal Chemistry|December 23, 2011
Novel 3-phenylpiperidine-4-carboxamides as highly potent and orally long-acting neurokinin-1 receptor antagonists with reduced CYP3A inductionJunya Shirai, Hideyuki Sugiyama, Shinji Morimoto, et al.
Journal of Medicinal Chemistry|April 20, 2012
Discovery of a novel pyrrole derivative 1-[5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine fumarate (TAK-438) as a potassium-competitive acid blocker (P-CAB)Yasuyoshi Arikawa, Haruyuki Nishida, Osamu Kurasawa, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|August 20, 2010
A noncompetitive BACE1 inhibitor TAK-070 ameliorates Abeta pathology and behavioral deficits in a mouse model of Alzheimer's diseaseHiroaki Fukumoto, Hideki Takahashi, Naoki Tarui, et al.
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