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Nutrition and Cancer|February 20, 2014
Theobromine, the primary methylxanthine found in Theobroma cacao, prevents malignant glioblastoma proliferation by negatively regulating phosphodiesterase-4, extracellular signal-regulated kinase, Akt/mammalian target of rapamycin kinase, and nuclear factor-kappa BNaotoshi Sugimoto, Shinji Miwa, Yoshiaki Hitomi, et al.
Temperature (Austin, Tex.)|May 27, 2016
β-amyloid infusion into lateral ventricle alters behavioral thermoregulation and attenuates acquired heat tolerance in ratsKentaro Matsuzaki, Masanori Katakura, Naotoshi Sugimoto, et al.
Cell Biology and Toxicology|September 10, 2014
Shiga toxin-2 enhances heat-shock-induced apoptotic cell death in cultured and primary glial cellsNaotoshi Sugimoto, Tomoko Toma, Masaki Shimizu, et al.
Plos One|June 20, 2017
Neural progenitor cell proliferation in the hypothalamus is involved in acquired heat tolerance in long-term heat-acclimated ratsKentaro Matsuzaki, Masanori Katakura, Naotoshi Sugimoto, et al.
Clinical and Experimental Nephrology|November 24, 2018
Interleukin-33/ST2 signaling contributes to the severity of hemolytic uremic syndrome induced by enterohemorrhagic Escherichia coliShimpei Yamada, Masaki Shimizu, Mondo Kuroda, et al.
Oncology Letters|August 20, 2019
Corticosterone inhibits the expression of cannabinoid receptor-1 and cannabinoid receptor agonist-induced decrease in cell viability in glioblastoma cellsNaotoshi Sugimoto, Hiroaki Ishibashi, Yoshibumi Ueda, et al.
Molecular Biology Reports|February 28, 2022
Effects of long-term treatment with dietary theobromine on rat skeletal musclesShoji Tanaka, Naotoshi Sugimoto, Takako Ohno-Shosaku, et al.
Cancer Chemotherapy and Pharmacology|December 10, 2016
Phase I clinical and pharmacokinetic study of S-1 plus oral leucovorin in patients with metastatic colorectal cancerTakayuki Yoshino, Ichinosuke Hyodo, Tomohiro Nishina, et al.
Journal of Biochemical and Molecular Toxicology|January 24, 2019
Heat attenuates sensitivity of mammalian cells to capsaicinNaotoshi Sugimoto, Kentaro Matsuzaki, Masanori Katakura, et al.
The Journal of Biological Chemistry|January 9, 2004
Blood lipid mediator sphingosine 1-phosphate potently stimulates platelet-derived growth factor-A and -B chain expression through S1P1-Gi-Ras-MAPK-dependent induction of Kruppel-like factor 5Soichiro Usui, Naotoshi Sugimoto, Noriko Takuwa, et al.
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