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Iscience|November 16, 2020
Ubiquitin Homeostasis Is Disrupted in TDP-43 and FUS Cell Models of ALSNatalie E Farrawell, Luke McAlary, Jeremy S Lum, et al.Human Molecular Genetics|May 23, 2023
ALS-linked CCNF variant disrupts motor neuron ubiquitin homeostasisNatalie E Farrawell, Monique Bax, Luke McAlary, et al.Cells|June 16, 2019
The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron DifferentiationMonique Bax, Jessie McKenna, Dzung Do-Ha, et al.Ebiomedicine|April 13, 2025
A polytherapy approach demonstrates therapeutic efficacy for the treatment of SOD1 associated amyotrophic lateral sclerosisJeremy S Lum, Mikayla L Brown, Natalie E Farrawell, et al.Scientific Reports|September 30, 2021
CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1G93A mice with a C57BL/6 backgroundJeremy S Lum, Mikayla L Brown, Natalie E Farrawell, et al.Nature Communications|November 10, 2025
Development of a targeted BioPROTAC degrader selective for misfolded SOD1Christen G Chisholm, Rachael Bartlett, Mikayla L Brown, et al.Neurobiology of Disease|March 1, 2022
TDP-43 is a ubiquitylation substrate of the SCFcyclin F complexStephanie L Rayner, Shu Yang, Natalie E Farrawell, et al.Pageof 2