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Neurobiology of Disease|May 19, 2019
Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrilsIsabella Russo, Alice Kaganovich, Jinhui Ding, et al.
Neurobiology of Disease|May 21, 2020
Sequential screening nominates the Parkinson's disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosisGeorge R Heaton, Natalie Landeck, Adamantios Mamais, et al.
Experimental & Molecular Medicine|November 19, 2025
Redirecting microglia phenotype via inhibition of NFAT1 ameliorates deficits in mouse model of synucleinopathiesMichiyo Iba, Yeon-Joo Lee, Somin Kwon, et al.
Science Advances|November 12, 2020
LRRK2 mediates tubulation and vesicle sorting from lysosomesLuis Bonet-Ponce, Alexandra Beilina, Chad D Williamson, et al.
Synapse (New York, N.Y.)|July 17, 2018
In vivo quantification of glial activation in minipigs overexpressing human α-synucleinThea Pinholt Lillethorup, Andreas Nørgaard Glud, Natalie Landeck, et al.
Scientific Reports|October 26, 2018
Longitudinal monoaminergic PET imaging of chronic proteasome inhibition in minipigsThea P Lillethorup, Andreas N Glud, Aage K O Alstrup, et al.
Molecular Neurodegeneration|September 9, 2020
Two C-terminal sequence variations determine differential neurotoxicity between human and mouse α-synucleinNatalie Landeck, Katherine E Strathearn, Daniel Ysselstein, et al.
Biorxiv : the Preprint Server for Biology|February 6, 2026
Inflammatory signaling differentially changes chromatin accessibility and gene expression of the PD- associated kinase LRRK2 between human and miceAlexandra Beilina, Jae-Hyeon Park, Natalie Landeck, et al.
Glia|October 12, 2020
Extracellular clusterin limits the uptake of α-synuclein fibrils by murine and human astrocytesAlice Filippini, Veronica Mutti, Gaia Faustini, et al.
Plos Biology|December 16, 2021
Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microgliaAdamantios Mamais, Jillian H Kluss, Luis Bonet-Ponce, et al.
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