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Trends in Biochemical Sciences|February 5, 2020
Miniproteins as a Powerful Modality in Drug DevelopmentZachary R Crook, Natalie W Nairn, James M OlsonBioconjugate Chemistry|October 7, 2015
Cysteine as a Monothiol Reducing Agent to Prevent Copper-Mediated Oxidation of Interferon Beta During PEGylation by CuAACNatalie W Nairn, Pauline A Bariola, Thomas J Graddis, et al.Bioconjugate Chemistry|September 20, 2012
Development of copper-catalyzed azide-alkyne cycloaddition for increased in vivo efficacy of interferon β-1b by site-specific PEGylationNatalie W Nairn, Kurt D Shanebeck, Aijun Wang, et al.Biorxiv : the Preprint Server for Biology|May 7, 2024
CYpHER: Catalytic extracellular targeted protein degradation with high potency and durable effectZachary R Crook, Gregory P Sevilla, Pamela Young, et al.Nature Communications|October 9, 2024
CYpHER: catalytic extracellular targeted protein degradation with high potency and durable effectZachary R Crook, Gregory P Sevilla, Pamela Young, et al.Protein Engineering, Design & Selection : PEDS|August 15, 2015
AZ17: a new bispecific drug targeting IL-6 and IL-23 with potential clinical use--improves psoriasis in a human xenograft transplantation modelKarin Stenderup, Cecilia Rosada, Kurt Shanebeck, et al.Science Translational Medicine|May 18, 2022
Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engagerZachary R Crook, Emily J Girard, Gregory P Sevilla, et al.Science Translational Medicine|March 6, 2020
A potent peptide-steroid conjugate accumulates in cartilage and reverses arthritis without evidence of systemic corticosteroid exposureMichelle L Cook Sangar, Emily J Girard, Gene Hopping, et al.Pageof 1