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Nature Reviews. Drug Discovery
|
August 25, 2022
Advances in covalent drug discovery
Lydia Boike, Nathaniel J Henning, Daniel K Nomura
Biochemical and Biophysical Research Communications
|
October 13, 2020
Comparison of the reaction of methylglyoxal (MGO) with murine and human amyloid beta (Aβ): Insights into a mechanism of Alzheimer's disease (AD)
Sydney O Shuster, Sebastian M Fica-Contreras, Jake S Hedges, et al.
Frontiers in Molecular Biosciences
|
June 9, 2020
Structure and Characterization of a Covalent Inhibitor of Src Kinase
Deepak Gurbani, Guangyan Du, Nathaniel J Henning, et al.
Journal of the American Chemical Society
|
January 7, 2022
Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications
Nathaniel J Henning, Andrew G Manford, Jessica N Spradlin, et al.
Journal of the American Chemical Society
|
September 14, 2023
Correction to "Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications"
Nathaniel J Henning, Andrew G Manford, Jessica N Spradlin, et al.
Angewandte Chemie (International Ed. in English)
|
April 29, 2021
Discovery of a Potent Degrader for Fibroblast Growth Factor Receptor 1/2
Guangyan Du, Jie Jiang, Qibiao Wu, et al.
Cell Chemical Biology
|
September 23, 2020
Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC
Lydia Boike, Alexander G Cioffi, Felix C Majewski, et al.
Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry
|
October 18, 2017
Glycation of Lys-16 and Arg-5 in amyloid-β and the presence of Cu<sup>2+</sup> play a major role in the oxidative stress mechanism of Alzheimer's disease
Sebastian M Fica-Contreras, Sydney O Shuster, Nathaniel D Durfee, et al.
Journal of Medicinal Chemistry
|
January 15, 2020
Structure-Based Design of a Potent and Selective Covalent Inhibitor for SRC Kinase That Targets a P-Loop Cysteine
Guangyan Du, Suman Rao, Deepak Gurbani, et al.
Cell Chemical Biology
|
September 7, 2022
Exploring the target scope of KEAP1 E3 ligase-based PROTACs
Guangyan Du, Jie Jiang, Nathaniel J Henning, et al.
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Showing results (1-10 of 12) with videos related to
Sort By:
Page
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Nature Reviews. Drug Discovery
|
August 25, 2022
Advances in covalent drug discovery
Lydia Boike, Nathaniel J Henning, Daniel K Nomura
Biochemical and Biophysical Research Communications
|
October 13, 2020
Comparison of the reaction of methylglyoxal (MGO) with murine and human amyloid beta (Aβ): Insights into a mechanism of Alzheimer's disease (AD)
Sydney O Shuster, Sebastian M Fica-Contreras, Jake S Hedges, et al.
Frontiers in Molecular Biosciences
|
June 9, 2020
Structure and Characterization of a Covalent Inhibitor of Src Kinase
Deepak Gurbani, Guangyan Du, Nathaniel J Henning, et al.
Journal of the American Chemical Society
|
January 7, 2022
Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications
Nathaniel J Henning, Andrew G Manford, Jessica N Spradlin, et al.
Journal of the American Chemical Society
|
September 14, 2023
Correction to "Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications"
Nathaniel J Henning, Andrew G Manford, Jessica N Spradlin, et al.
Angewandte Chemie (International Ed. in English)
|
April 29, 2021
Discovery of a Potent Degrader for Fibroblast Growth Factor Receptor 1/2
Guangyan Du, Jie Jiang, Qibiao Wu, et al.
Cell Chemical Biology
|
September 23, 2020
Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC
Lydia Boike, Alexander G Cioffi, Felix C Majewski, et al.
Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry
|
October 18, 2017
Glycation of Lys-16 and Arg-5 in amyloid-β and the presence of Cu<sup>2+</sup> play a major role in the oxidative stress mechanism of Alzheimer's disease
Sebastian M Fica-Contreras, Sydney O Shuster, Nathaniel D Durfee, et al.
Journal of Medicinal Chemistry
|
January 15, 2020
Structure-Based Design of a Potent and Selective Covalent Inhibitor for SRC Kinase That Targets a P-Loop Cysteine
Guangyan Du, Suman Rao, Deepak Gurbani, et al.
Cell Chemical Biology
|
September 7, 2022
Exploring the target scope of KEAP1 E3 ligase-based PROTACs
Guangyan Du, Jie Jiang, Nathaniel J Henning, et al.
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of 2