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Bioorganic & Medicinal Chemistry Letters|December 3, 2014
Discovery and optimization of novel small-molecule HIV-1 entry inhibitors using field-based virtual screening and bioisosteric replacementMarina Tuyishime, Matt Danish, Amy Princiotto, et al.
Bioorganic & Medicinal Chemistry|December 21, 2010
Design, synthesis and biological evaluation of small molecule inhibitors of CD4-gp120 binding based on virtual screeningJudith M Lalonde, Mark A Elban, Joel R Courter, et al.
Journal of Virology|December 23, 2016
Residues in the gp41 Ectodomain Regulate HIV-1 Envelope Glycoprotein Conformational Transitions Induced by gp120-Directed InhibitorsBeatriz Pacheco, Nirmin Alsahafi, Olfa Debbeche, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 31, 2004
Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteinsZhihai Si, Navid Madani, Jason M Cox, et al.
Journal of Virology|August 9, 2019
Strain-Dependent Activation and Inhibition of Human Immunodeficiency Virus Entry by a Specific PF-68742 StereoisomerConnie Zhao, Amy M Princiotto, Hanh T Nguyen, et al.
ACS Medicinal Chemistry Letters|January 19, 2023
Structural and Functional Characterization of Indane-Core CD4-Mimetic Compounds Substituted with Heterocyclic AminesCheyenne Chaplain, Christopher J Fritschi, Saumya Anang, et al.
ACS Medicinal Chemistry Letters|March 18, 2016
Small-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry InhibitionBruno Melillo, Shuaiyi Liang, Jongwoo Park, et al.
ACS Medicinal Chemistry Letters|May 14, 2013
Structure-Based Design and Synthesis of an HIV-1 Entry Inhibitor Exploiting X-Ray and Thermodynamic CharacterizationJudith M Lalonde, Matthew Le-Khac, David M Jones, et al.
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