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International Journal of Molecular Sciences|August 20, 2015
Structure-Based Optimization of Inhibitors of the Aspartic Protease EndothiapepsinAlwin M Hartman, Milon Mondal, Nedyalka Radeva, et al.Angewandte Chemie (International Ed. in English)|July 13, 2016
Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin: Fragment-Based Drug Design Facilitated by Dynamic Combinatorial ChemistryMilon Mondal, Nedyalka Radeva, Hugo Fanlo-Virgós, et al.Angewandte Chemie (International Ed. in English)|February 18, 2014
Structure-based design of inhibitors of the aspartic protease endothiapepsin by exploiting dynamic combinatorial chemistryMilon Mondal, Nedyalka Radeva, Helene Köster, et al.Angewandte Chemie (International Ed. in English)|January 19, 2017
A False-Positive Screening Hit in Fragment-Based Lead Discovery: Watch out for the Red HerringJonathan Cramer, Johannes Schiebel, Tobias Wulsdorf, et al.ACS Chemical Biology|March 31, 2016
Six Biophysical Screening Methods Miss a Large Proportion of Crystallographically Discovered Fragment Hits: A Case StudyJohannes Schiebel, Nedyalka Radeva, Stefan G Krimmer, et al.Journal of Medicinal Chemistry|July 28, 2016
Experimental Active-Site Mapping by Fragments: Hot Spots Remote from the Catalytic Center of EndothiapepsinNedyalka Radeva, Stefan G Krimmer, Martin Stieler, et al.Structure (London, England : 1993)|July 26, 2016
High-Throughput Crystallography: Reliable and Efficient Identification of Fragment HitsJohannes Schiebel, Stefan G Krimmer, Karine Röwer, et al.Journal of Medicinal Chemistry|October 12, 2016
Active Site Mapping of an Aspartic Protease by Multiple Fragment Crystal Structures: Versatile Warheads To Address a Catalytic DyadNedyalka Radeva, Johannes Schiebel, Xiaojie Wang, et al.Chemmedchem|August 12, 2015
One Question, Multiple Answers: Biochemical and Biophysical Screening Methods Retrieve Deviating Fragment Hit ListsJohannes Schiebel, Nedyalka Radeva, Helene Köster, et al.Pageof 1