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The Journal of Biological Chemistry|December 11, 2013
Rhes, a striatal-selective protein implicated in Huntington disease, binds beclin-1 and activates autophagyRobert G Mealer, Alexandra J Murray, Neelam Shahani, et al.Science Advances|March 23, 2022
Rhes protein transits from neuron to neuron and facilitates mutant huntingtin spreading in the brainUri Nimrod Ramírez-Jarquín, Manish Sharma, Neelam Shahani, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|March 18, 2005
Insulin-like growth factor 1 inhibits extracellular signal-regulated kinase to promote neuronal survival via the phosphatidylinositol 3-kinase/protein kinase A/c-Raf pathwaySrinivasa Subramaniam, Neelam Shahani, Jens Strelau, et al.Neurobiology of Disease|June 7, 2015
Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington's diseaseSupriya Swarnkar, Youjun Chen, William M Pryor, et al.The Journal of Biological Chemistry|December 26, 2013
Rheb GTPase regulates β-secretase levels and amyloid β generationNeelam Shahani, William Pryor, Supriya Swarnkar, et al.Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases|October 30, 2004
(-)-Deprenyl alleviates the degenerative changes induced in the neonatal rat spinal cord by CSF from amyotrophic lateral sclerosis patientsNeelam Shahani, M Gourie-Devi, A Nalini, et al.Molecular & Cellular Proteomics : MCP|March 6, 2024
Ribosome Profiling and Mass Spectrometry Reveal Widespread Mitochondrial Translation Defects in a Striatal Cell Model of Huntington DiseaseSunayana Dagar, Manish Sharma, George Tsaprailis, et al.Journal of Neural Transmission (Vienna, Austria : 1996)|November 12, 2010
Down regulation of trophic factors in neonatal rat spinal cord after administration of cerebrospinal fluid from sporadic amyotrophic lateral sclerosis patientsP Deepa, Neelam Shahani, Phalguni Anand Alladi, et al.Science Signaling|October 30, 2014
Huntingtin promotes mTORC1 signaling in the pathogenesis of Huntington's diseaseWilliam M Pryor, Marta Biagioli, Neelam Shahani, et al.Human Molecular Genetics|May 22, 2016
Allele-specific regulation of mutant Huntingtin by Wig1, a downstream target of p53Sun-Hong Kim, Neelam Shahani, Byoung-Ii Bae, et al.Pageof 4