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Bioorganic & Medicinal Chemistry Letters|September 21, 2015
Non-basic azolotriazinone MCHR1 antagonists for the treatment of obesity: An empirical brain-exposures-driven candidate selection for in vivo efficacy studiesPratik Devasthale, Wei Wang, James Mignone, et al.Bioorganic & Medicinal Chemistry Letters|May 30, 2015
Dihydropyrrolopyrazol-6-one MCHR1 antagonists for the treatment of obesity: Insights on in vivo efficacy from a novel FLIPR assay setupPratik Devasthale, Wei Wang, Andres S Hernandez, et al.Bioorganic & Medicinal Chemistry Letters|February 18, 2015
Synthesis and biological evaluation of novel pyrrolidine acid analogs as potent dual PPARα/γ agonistsHao Zhang, Charles Z Ding, Zhi Lai, et al.Journal of Medicinal Chemistry|November 2, 2007
Discovery of a tetrazole-based growth hormone secretagogue: 4-(hydroxybutyl)carbamic acid 2-{5-[1-(2-amino-2-methylpropionylamino)-2- benzyloxyethyl]tetrazol-1-yl}ethyl ester (BMS-317180)Jun Li, Stephanie Y Chen, James J Li, et al.Journal of Medicinal Chemistry|August 29, 2014
Identification of a nonbasic melanin hormone receptor 1 antagonist as an antiobesity clinical candidateWilliam N Washburn, Mark Manfredi, Pratik Devasthale, et al.Pageof 3