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Nature Communications
|
July 26, 2020
Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models
Hyoung Kim, Haineng Xu, Erin George, et al.
Journal of Aerosol Medicine and Pulmonary Drug Delivery
|
February 10, 2016
Preclinical Experimental and Mathematical Approaches for Assessing Effective Doses of Inhaled Drugs, Using Mometasone to Support Human Dose Predictions
Michael Caniga, Antonio Cabal, Khamir Mehta, et al.
Cell Reports
|
September 27, 2018
BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance
Joseph Nacson, John J Krais, Andrea J Bernhardy, et al.
Cell Reports
|
November 1, 2018
BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance
Joseph Nacson, John J Krais, Andrea J Bernhardy, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
October 3, 2013
Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance
Neil Johnson, Shawn F Johnson, Wei Yao, et al.
Journal of Medicinal Chemistry
|
October 22, 2025
RTx-303, an Orally Bioavailable Polθ Polymerase Inhibitor That Potentiates PARP Inhibitors in BRCA Mutant Tumors
Gurushankar Chandramouly, William Fried, John Gordon, et al.
Nature Communications
|
November 24, 2023
Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities
John J Krais, David J Glass, Ilse Chudoba, et al.
Cell Reports
|
June 14, 2018
Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic Lethality in BRCA-Deficient Tumor Cells
Katherine Sullivan-Reed, Elisabeth Bolton-Gillespie, Yashodhara Dasgupta, et al.
Nature Communications
|
April 5, 2024
Discovery of a small-molecule inhibitor that traps Polθ on DNA and synergizes with PARP inhibitors
William Fried, Mrityunjay Tyagi, Leonid Minakhin, et al.
JCI Insight
|
January 19, 2017
A patient-derived-xenograft platform to study BRCA-deficient ovarian cancers
Erin George, Hyoung Kim, Clemens Krepler, et al.
Page
of 16
Search research articles
Search
Showing results (131-140 of 152) with videos related to
Sort By:
Page
of 16
Nature Communications
|
July 26, 2020
Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models
Hyoung Kim, Haineng Xu, Erin George, et al.
Journal of Aerosol Medicine and Pulmonary Drug Delivery
|
February 10, 2016
Preclinical Experimental and Mathematical Approaches for Assessing Effective Doses of Inhaled Drugs, Using Mometasone to Support Human Dose Predictions
Michael Caniga, Antonio Cabal, Khamir Mehta, et al.
Cell Reports
|
September 27, 2018
BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance
Joseph Nacson, John J Krais, Andrea J Bernhardy, et al.
Cell Reports
|
November 1, 2018
BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance
Joseph Nacson, John J Krais, Andrea J Bernhardy, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
October 3, 2013
Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance
Neil Johnson, Shawn F Johnson, Wei Yao, et al.
Journal of Medicinal Chemistry
|
October 22, 2025
RTx-303, an Orally Bioavailable Polθ Polymerase Inhibitor That Potentiates PARP Inhibitors in BRCA Mutant Tumors
Gurushankar Chandramouly, William Fried, John Gordon, et al.
Nature Communications
|
November 24, 2023
Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities
John J Krais, David J Glass, Ilse Chudoba, et al.
Cell Reports
|
June 14, 2018
Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic Lethality in BRCA-Deficient Tumor Cells
Katherine Sullivan-Reed, Elisabeth Bolton-Gillespie, Yashodhara Dasgupta, et al.
Nature Communications
|
April 5, 2024
Discovery of a small-molecule inhibitor that traps Polθ on DNA and synergizes with PARP inhibitors
William Fried, Mrityunjay Tyagi, Leonid Minakhin, et al.
JCI Insight
|
January 19, 2017
A patient-derived-xenograft platform to study BRCA-deficient ovarian cancers
Erin George, Hyoung Kim, Clemens Krepler, et al.
Page
of 16