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Bioorganic & Medicinal Chemistry
|
November 24, 2019
High content phenotypic screening identifies serotonin receptor modulators with selective activity upon breast cancer cell cycle and cytokine signaling pathways
Scott J Warchal, John C Dawson, Emelie Shepherd, et al.
Clinical and Translational Medicine
|
February 5, 2023
YAP/TAZ activation predicts clinical outcomes in mesothelioma and is conserved in in vitro model of driver mutations
Richard Cunningham, Siyang Jia, Krishna Purohit, et al.
RSC Medicinal Chemistry
|
November 4, 2024
Ligand-centred phenotype-driven development of potent kinase inhibitors against oesophageal cancer
Cecilia C Ayala-Aguilera, Yang Ge, Álvaro Lorente-Macías, et al.
Journal of Medicinal Chemistry
|
April 13, 2026
Discovery of a Highly Potent and Selective mTOR Inhibitor that Strongly Suppresses Glioblastoma Multiforme Cell Growth
Álvaro Lorente-Macías, Jonathon Mok, John C Dawson, et al.
Pharmaceutics
|
December 7, 2013
Live cell in vitro and in vivo imaging applications: accelerating drug discovery
Beverley Isherwood, Paul Timpson, Ewan J McGhee, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
May 23, 2020
High-Content Phenotypic Profiling in Esophageal Adenocarcinoma Identifies Selectively Active Pharmacological Classes of Drugs for Repurposing and Chemical Starting Points for Novel Drug Discovery
Rebecca E Hughes, Richard J R Elliott, Alison F Munro, et al.
Cancer Research
|
March 26, 2009
Real-time study of E-cadherin and membrane dynamics in living animals: implications for disease modeling and drug development
Alan Serrels, Paul Timpson, Marta Canel, et al.
Journal of Biomolecular Screening
|
October 11, 2013
High-content analysis to leverage a robust phenotypic profiling approach to vascular modulation
Beverley J Isherwood, Rebecca E Walls, Mark E Roberts, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
June 3, 2021
Application of a High-Content Screening Assay Utilizing Primary Human Lung Fibroblasts to Identify Antifibrotic Drugs for Rapid Repurposing in COVID-19 Patients
John A Marwick, Richard J R Elliott, James Longden, et al.
Disease Models & Mechanisms
|
May 11, 2021
Automated in vivo drug screen in zebrafish identifies synapse-stabilising drugs with relevance to spinal muscular atrophy
Ana-Maria Oprişoreanu, Hannah L Smith, Sophia Krix, et al.
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of 12
Search research articles
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Showing results (41-50 of 112) with videos related to
Sort By:
Page
of 12
Bioorganic & Medicinal Chemistry
|
November 24, 2019
High content phenotypic screening identifies serotonin receptor modulators with selective activity upon breast cancer cell cycle and cytokine signaling pathways
Scott J Warchal, John C Dawson, Emelie Shepherd, et al.
Clinical and Translational Medicine
|
February 5, 2023
YAP/TAZ activation predicts clinical outcomes in mesothelioma and is conserved in in vitro model of driver mutations
Richard Cunningham, Siyang Jia, Krishna Purohit, et al.
RSC Medicinal Chemistry
|
November 4, 2024
Ligand-centred phenotype-driven development of potent kinase inhibitors against oesophageal cancer
Cecilia C Ayala-Aguilera, Yang Ge, Álvaro Lorente-Macías, et al.
Journal of Medicinal Chemistry
|
April 13, 2026
Discovery of a Highly Potent and Selective mTOR Inhibitor that Strongly Suppresses Glioblastoma Multiforme Cell Growth
Álvaro Lorente-Macías, Jonathon Mok, John C Dawson, et al.
Pharmaceutics
|
December 7, 2013
Live cell in vitro and in vivo imaging applications: accelerating drug discovery
Beverley Isherwood, Paul Timpson, Ewan J McGhee, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
May 23, 2020
High-Content Phenotypic Profiling in Esophageal Adenocarcinoma Identifies Selectively Active Pharmacological Classes of Drugs for Repurposing and Chemical Starting Points for Novel Drug Discovery
Rebecca E Hughes, Richard J R Elliott, Alison F Munro, et al.
Cancer Research
|
March 26, 2009
Real-time study of E-cadherin and membrane dynamics in living animals: implications for disease modeling and drug development
Alan Serrels, Paul Timpson, Marta Canel, et al.
Journal of Biomolecular Screening
|
October 11, 2013
High-content analysis to leverage a robust phenotypic profiling approach to vascular modulation
Beverley J Isherwood, Rebecca E Walls, Mark E Roberts, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
June 3, 2021
Application of a High-Content Screening Assay Utilizing Primary Human Lung Fibroblasts to Identify Antifibrotic Drugs for Rapid Repurposing in COVID-19 Patients
John A Marwick, Richard J R Elliott, James Longden, et al.
Disease Models & Mechanisms
|
May 11, 2021
Automated in vivo drug screen in zebrafish identifies synapse-stabilising drugs with relevance to spinal muscular atrophy
Ana-Maria Oprişoreanu, Hannah L Smith, Sophia Krix, et al.
Page
of 12