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Nature Communications|February 9, 2016
KRAS insertion mutations are oncogenic and exhibit distinct functional propertiesYasmine White, Aditi Bagchi, Jessica Van Ziffle, et al.Bioorganic & Medicinal Chemistry Letters|October 19, 2021
Chemical proteomic analysis of palmostatin beta-lactone analogs that affect N-Ras palmitoylationRadu M Suciu, Irungu K Luvaga, Akram Hazeen, et al.Blood|April 21, 2024
BCR::ABL1 kinase N-lobe mutants confer moderate to high degrees of resistance to asciminibAriel Leyte-Vidal, Diego Garrido Ruiz, RosaAnna DeFilippis, et al.Cancer Chemotherapy and Pharmacology|April 24, 2013
Analysis of the potential effect of ponatinib on the QTc interval in patients with refractory hematological malignanciesDaryl Sonnichsen, David J Dorer, Jorge Cortes, et al.Haematologica|February 9, 2010
Potent, transient inhibition of BCR-ABL with dasatinib 100 mg daily achieves rapid and durable cytogenetic responses and high transformation-free survival rates in chronic phase chronic myeloid leukemia patients with resistance, suboptimal response or intolerance to imatinibNeil P Shah, Dong-Wook Kim, Hagop Kantarjian, et al.Cancer Research|January 21, 2006
Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora kinase inhibitor VX-680Matthew A Young, Neil P Shah, Luke H Chao, et al.American Journal of Hematology|February 5, 2010
Dasatinib 140 mg once daily versus 70 mg twice daily in patients with Ph-positive acute lymphoblastic leukemia who failed imatinib: Results from a phase 3 studyMichael B Lilly, Oliver G Ottmann, Neil P Shah, et al.Cell Reports|April 11, 2019
High-Complexity shRNA Libraries and PI3 Kinase Inhibition in Cancer: High-Fidelity Synthetic Lethality PredictionsMarsilius Mues, Laila Karra, Damia Romero-Moya, et al.Blood|December 29, 2006
K-RasG12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cellsMargaret E M Van Meter, Ernesto Díaz-Flores, Joehleen A Archard, et al.Nature Chemical Biology|March 4, 2014
Dual kinase-bromodomain inhibitors for rationally designed polypharmacologyPietro Ciceri, Susanne Müller, Alison O'Mahony, et al.Pageof 21