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CPT: Pharmacometrics & Systems Pharmacology
|
February 15, 2024
In silico modeling and simulation of organ-on-a-chip systems to support data analysis and a priori experimental design
Nicoló Milani, Neil Parrott, Aleksandra Galetin, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
|
March 1, 2014
Applications of a 7-day Caco-2 cell model in drug discovery and development
Ying Peng, Preeti Yadava, Aki T Heikkinen, et al.
Clinical Pharmacology and Therapeutics
|
July 18, 2024
PBPK Modeling of Entrectinib and Its Active Metabolite to Derive Dose Adjustments in Pediatric Populations Co-Administered with CYP3A4 Inhibitors
Kenichi Umehara, Neil Parrott, Emilie Schindler, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems
|
August 25, 2022
A translational strategy employing physiologically based modelling to predict the pharmacological active dose of RO7119929, an oral prodrug of a targeted cancer immunotherapy TLR7 agonist
Caroline Rynn, Kenichi Umehara, Tianyi Jiang, et al.
Pharmaceutical Research
|
July 30, 2013
In vitro and ex vivo investigation of the impact of luminal lipid phases on passive permeability of lipophilic small molecules using PAMPA
Constantinos Markopoulos, Georgios Imanidis, Maria Vertzoni, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
December 3, 2023
Evaluation of the potential impact on pharmacokinetics of various cytochrome P450 substrates of increasing IL-6 levels following administration of the T-cell bispecific engager glofitamab
Nassim Djebli, Neil Parrott, Felix Jaminion, et al.
International Journal of Pharmaceutics: X
|
March 19, 2025
Investigating the effect of whey and casein proteins on drug solubility from a paediatric drug absorption perspective
Matthias Van der Veken, Joachim Brouwers, Neil Parrott, et al.
The AAPS Journal
|
June 20, 2019
Impact of Intracellular Concentrations on Metabolic Drug-Drug Interaction Studies
Andrea Treyer, Mohammed Ullah, Neil Parrott, et al.
The AAPS Journal
|
June 18, 2021
Use of Physiologically Based Pharmacokinetic Modeling for Predicting Drug-Food Interactions: Recommendations for Improving Predictive Performance of Low Confidence Food Effect Models
Christian Wagner, Filippos Kesisoglou, Xavier J H Pepin, et al.
Clinical Pharmacokinetics
|
February 8, 2019
Physiologically Based Pharmacokinetic Modelling for First-In-Human Predictions: An Updated Model Building Strategy Illustrated with Challenging Industry Case Studies
Neil A Miller, Micaela B Reddy, Aki T Heikkinen, et al.
Page
of 13
Search research articles
Search
Showing results (31-40 of 125) with videos related to
Sort By:
Page
of 13
CPT: Pharmacometrics & Systems Pharmacology
|
February 15, 2024
In silico modeling and simulation of organ-on-a-chip systems to support data analysis and a priori experimental design
Nicoló Milani, Neil Parrott, Aleksandra Galetin, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
|
March 1, 2014
Applications of a 7-day Caco-2 cell model in drug discovery and development
Ying Peng, Preeti Yadava, Aki T Heikkinen, et al.
Clinical Pharmacology and Therapeutics
|
July 18, 2024
PBPK Modeling of Entrectinib and Its Active Metabolite to Derive Dose Adjustments in Pediatric Populations Co-Administered with CYP3A4 Inhibitors
Kenichi Umehara, Neil Parrott, Emilie Schindler, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems
|
August 25, 2022
A translational strategy employing physiologically based modelling to predict the pharmacological active dose of RO7119929, an oral prodrug of a targeted cancer immunotherapy TLR7 agonist
Caroline Rynn, Kenichi Umehara, Tianyi Jiang, et al.
Pharmaceutical Research
|
July 30, 2013
In vitro and ex vivo investigation of the impact of luminal lipid phases on passive permeability of lipophilic small molecules using PAMPA
Constantinos Markopoulos, Georgios Imanidis, Maria Vertzoni, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
December 3, 2023
Evaluation of the potential impact on pharmacokinetics of various cytochrome P450 substrates of increasing IL-6 levels following administration of the T-cell bispecific engager glofitamab
Nassim Djebli, Neil Parrott, Felix Jaminion, et al.
International Journal of Pharmaceutics: X
|
March 19, 2025
Investigating the effect of whey and casein proteins on drug solubility from a paediatric drug absorption perspective
Matthias Van der Veken, Joachim Brouwers, Neil Parrott, et al.
The AAPS Journal
|
June 20, 2019
Impact of Intracellular Concentrations on Metabolic Drug-Drug Interaction Studies
Andrea Treyer, Mohammed Ullah, Neil Parrott, et al.
The AAPS Journal
|
June 18, 2021
Use of Physiologically Based Pharmacokinetic Modeling for Predicting Drug-Food Interactions: Recommendations for Improving Predictive Performance of Low Confidence Food Effect Models
Christian Wagner, Filippos Kesisoglou, Xavier J H Pepin, et al.
Clinical Pharmacokinetics
|
February 8, 2019
Physiologically Based Pharmacokinetic Modelling for First-In-Human Predictions: An Updated Model Building Strategy Illustrated with Challenging Industry Case Studies
Neil A Miller, Micaela B Reddy, Aki T Heikkinen, et al.
Page
of 13