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Journal of Medicinal Chemistry|December 21, 2013
Substituted 2-phenylimidazopyridines: a new class of drug leads for human African trypanosomiasisHari Babu Tatipaka, J Robert Gillespie, Arnab K Chatterjee, et al.Journal of Medicinal Chemistry|December 14, 2011
Discovery of a novel class of orally active trypanocidal N-myristoyltransferase inhibitorsStephen Brand, Laura A T Cleghorn, Stuart P McElroy, et al.Journal of Medicinal Chemistry|November 21, 2014
Lead optimization of a pyrazole sulfonamide series of Trypanosoma brucei N-myristoyltransferase inhibitors: identification and evaluation of CNS penetrant compounds as potential treatments for stage 2 human African trypanosomiasisStephen Brand, Neil R Norcross, Stephen Thompson, et al.Journal of Medicinal Chemistry|November 10, 2023
Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular ActivitySimon R Green, Caroline Wilson, Thomas C Eadsforth, et al.Journal of Medicinal Chemistry|September 16, 2016
Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo EfficacyBeatriz Baragaña, Neil R Norcross, Caroline Wilson, et al.Chemmedchem|June 13, 2019
Substituted Aminoacetamides as Novel Leads for Malaria TreatmentNeil R Norcross, Caroline Wilson, Beatriz Baragaña, et al.Journal of Medicinal Chemistry|June 18, 2016
Trisubstituted Pyrimidines as Efficacious and Fast-Acting AntimalarialsNeil R Norcross, Beatriz Baragaña, Caroline Wilson, et al.Science Translational Medicine|October 23, 2024
Cryptosporidium lysyl-tRNA synthetase inhibitors define the interplay between solubility and permeability required to achieve efficacyNicola Caldwell, Caroline Peet, Peter Miller, et al.Journal of Medicinal Chemistry|June 2, 2026
Structure-Guided Optimization of Novel Inhibitors of Plasmodium Lysyl-tRNA Synthetase with Multistage Activity against Malaria ParasitesBarbara Forte, Fiona Bellany, Peter S Campbell, et al.Nature|June 19, 2015
A novel multiple-stage antimalarial agent that inhibits protein synthesisBeatriz Baragaña, Irene Hallyburton, Marcus C S Lee, et al.Pageof 3