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The Journal of Biological Chemistry|February 20, 2009
Knockdown of Ron kinase inhibits mutant phosphatidylinositol 3-kinase and reduces metastasis in human colon carcinomaJing Wang, Ashwani Rajput, Julie L C Kan, et al.
Molecular Cancer Therapeutics|June 16, 2011
Preclinical characterization of OSI-027, a potent and selective inhibitor of mTORC1 and mTORC2: distinct from rapamycinShripad V Bhagwat, Prafulla C Gokhale, Andrew P Crew, et al.
Bioorganic & Medicinal Chemistry|November 7, 2007
Novel 2-phenylquinolin-7-yl-derived imidazo[1,5-a]pyrazines as potent insulin-like growth factor-I receptor (IGF-IR) inhibitorsMark J Mulvihill, Qun-Sheng Ji, Heather R Coate, et al.
Bioorganic & Medicinal Chemistry Letters|March 1, 2006
3-[6-(2-Dimethylamino-1-imidazol-1-yl-butyl)-naphthalen-2-yloxy]-2,2-dimethyl-propionic acid as a highly potent and selective retinoic acid metabolic blocking agentMark J Mulvihill, Julie L C Kan, Andrew Cooke, et al.
Plos One|July 7, 2012
NOTCH1 signaling promotes human T-cell acute lymphoblastic leukemia initiating cell regeneration in supportive nichesWenxue Ma, Alejandro Gutierrez, Daniel J Goff, et al.
Bioorganic & Medicinal Chemistry Letters|March 1, 2011
Imidazo[1,5-a]pyrazines: orally efficacious inhibitors of mTORC1 and mTORC2Andrew P Crew, Shripad V Bhagwat, Hanqing Dong, et al.
Nature Genetics|November 1, 2011
Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancerKai Wang, Junsuo Kan, Siu Tsan Yuen, et al.
Lancet (London, England)|January 15, 2017
Safety, tolerability, and antiviral effect of RG-101 in patients with chronic hepatitis C: a phase 1B, double-blind, randomised controlled trialMeike H van der Ree, J Marleen de Vree, Femke Stelma, et al.
Cancer Research|January 21, 2006
OSI-930: a novel selective inhibitor of Kit and kinase insert domain receptor tyrosine kinases with antitumor activity in mouse xenograft modelsAndrew J Garton, Andrew P A Crew, Maryland Franklin, et al.
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