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Expert Opinion on Therapeutic Targets|April 2, 2003
MAPKs: new targets for neurodegenerationSarah J Harper, Neil WilkieArchives of Biochemistry and Biophysics|May 24, 2005
Substituting c-Jun N-terminal kinase-3 (JNK3) ATP-binding site amino acid residues with their p38 counterparts affects binding of JNK- and p38-selective inhibitorsMichael Fricker, Philip Lograsso, Semantha Ellis, et al.The Journal of Pharmacology and Experimental Therapeutics|November 14, 2006
The novel gamma secretase inhibitor N-[cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide (MRK-560) reduces amyloid plaque deposition without evidence of notch-related pathology in the Tg2576 mouseJonathan D Best, David W Smith, Michael A Reilly, et al.Pageof 1