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Nature Communications|January 11, 2019
Structure and inhibition mechanism of the catalytic domain of human squalene epoxidaseAnil K Padyana, Stefan Gross, Lei Jin, et al.
Bioorganic & Medicinal Chemistry Letters|August 3, 2010
SAR studies of non-zinc-chelating MMP-13 inhibitors: improving selectivity and metabolic stabilityDonghong Amy Gao, Zhaoming Xiong, Alexander Heim-Riether, et al.
Journal of Medicinal Chemistry|March 16, 2022
Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious LeadsMingzong Li, Zenon Konteatis, Nelamangala Nagaraja, et al.
Nature Communications|January 11, 2019
A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibitionChristopher E Mahoney, David Pirman, Victor Chubukov, et al.
Molecular Cancer Therapeutics|October 21, 2020
Selective Vulnerability to Pyrimidine Starvation in Hematologic Malignancies Revealed by AG-636, a Novel Clinical-Stage Inhibitor of Dihydroorotate DehydrogenaseGabrielle McDonald, Victor Chubukov, John Coco, et al.
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