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Cells|October 28, 2025
Biomarker-Based Pharmacological Characterization of ENX-102, a Novel α2/3/5 Subtype-Selective GABAA Receptor Positive Allo-Steric Modulator: Translational Insights from Rodent and Human StudiesPauline Nettesheim, Krishna C Vadodaria, Kimberly E Vanover, et al.Ebiomedicine|November 28, 2025
First-in-human high dose AAV9 intrathecal gene therapy for paediatric CLN7 disease: a phase 1, open-label, single ascending dose, non-randomised clinical trialBenjamin M Greenberg, Berge Minassian, Souad Messahel, et al.American Journal of Respiratory Cell and Molecular Biology|July 23, 2024
Enzymatic Modulation of the Pulmonary Glycocalyx Enhances Susceptibility to Streptococcus pneumoniaeCengiz Goekeri, Kerstin A K Linke, Karen Hoffmann, et al.Toxicological Sciences : an Official Journal of the Society of Toxicology|April 16, 2004
Gene expression profiling of rat livers reveals indicators of potential adverse effectsAlexandra N Heinloth, Richard D Irwin, Gary A Boorman, et al.Bioorganic & Medicinal Chemistry Letters|March 30, 2007
Discovery of a novel small molecule binding site of human survivinMichael D Wendt, Chaohong Sun, Aaron Kunzer, et al.Purinergic Signalling|July 20, 2021
Pro- and anti-inflammatory macrophages express a sub-type specific purinergic receptor profileJ Merz, A Nettesheim, S von Garlen, et al.Journal of Medicinal Chemistry|January 20, 2006
Discovery of a potent inhibitor of the antiapoptotic protein Bcl-xL from NMR and parallel synthesisAndrew M Petros, Jurgen Dinges, David J Augeri, et al.Circulation|August 21, 2023
Improved Cardiac Function in Postischemic Rats Using an Optimized Cardiac Reprogramming Cocktail Delivered in a Single Novel Adeno-Associated VirusHuanyu Zhou, Jin Yang, Chetan Srinath, et al.Journal of Medicinal Chemistry|June 23, 2006
Discovery and optimization of anthranilic acid sulfonamides as inhibitors of methionine aminopeptidase-2: a structural basis for the reduction of albumin bindingGeorge S Sheppard, Jieyi Wang, Megumi Kawai, et al.Nature|May 20, 2005
An inhibitor of Bcl-2 family proteins induces regression of solid tumoursTilman Oltersdorf, Steven W Elmore, Alexander R Shoemaker, et al.Pageof 26