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Bioorganic & Medicinal Chemistry Letters|October 10, 2002
Novel nucleotide phosphonate analogues with potent antitumor activityMonica Bubenik, Rabindra Rej, Nghe Nguyen-Ba, et al.Molecular Cancer Therapeutics|December 14, 2002
BCH-1868 [(-)-2-R-dihydroxyphosphinoyl-5-(S)-(guanin-9'-yl-methyl) tetrahydrofuran]: a cyclic nucleoside phosphonate with antitumor activityLorraine Leblond, Giorgio Attardo, Bettina Hamelin, et al.The Journal of Biological Chemistry|January 2, 2003
Non-nucleoside analogue inhibitors bind to an allosteric site on HCV NS5B polymerase. Crystal structures and mechanism of inhibitionMeitian Wang, Kenneth K-S Ng, Maia M Cherney, et al.Bioorganic & Medicinal Chemistry Letters|September 3, 2003
Further SAR studies on novel small molecule inhibitors of the hepatitis C (HCV) NS5B polymeraseT Jagadeeswar Reddy, Laval Chan, Nathalie Turcotte, et al.Journal of Medicinal Chemistry|April 4, 2003
Identification of N,N-disubstituted phenylalanines as a novel class of inhibitors of hepatitis C NS5B polymeraseLaval Chan, T Jagadeeswar Reddy, Mélanie Proulx, et al.Bioorganic & Medicinal Chemistry Letters|September 30, 2004
HCV NS5B polymerase-bound conformation of a soluble sulfonamide inhibitor by 2D transferred NOESYConstantin G Yannopoulos, Ping Xu, Feng Ni, et al.Bioorganic & Medicinal Chemistry Letters|January 27, 2004
Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 1: SulfonamidesLaval Chan, Sanjoy K Das, T Jagadeeswar Reddy, et al.Bioorganic & Medicinal Chemistry Letters|January 27, 2004
Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 2: tertiary amidesLaval Chan, Oswy Pereira, T Jagadeeswar Reddy, et al.Pageof 1