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Viruses|June 28, 2023
Querying Recombination Junctions of Replication-Competent Adeno-Associated Viruses in Gene Therapy Vector Preparations with Single Molecule, Real-Time SequencingMitchell Yip, Jing Chen, Yan Zhi, et al.Human Gene Therapy|September 30, 2022
Direct ITR-to-ITR Nanopore Sequencing of AAV Vector GenomesSuk Namkung, Ngoc Tam Tran, Sangeetha Manokaran, et al.Gene Therapy|October 6, 2021
Rational engineering of a functional CpG-free ITR for AAV gene therapyXiufang Pan, Yongping Yue, Maria Boftsi, et al.Molecular Therapy. Methods & Clinical Development|August 11, 2020
AAV-Genome Population Sequencing of Vectors Packaging CRISPR Components Reveals Design-Influenced HeterogeneityNgoc Tam Tran, Cheryl Heiner, Kristina Weber, et al.Human Gene Therapy|March 16, 2022
Human and Insect Cell-Produced Recombinant Adeno-Associated Viruses Show Differences in Genome HeterogeneityNgoc Tam Tran, Emilie Lecomte, Sylvie Saleun, et al.Molecular Therapy : the Journal of the American Society of Gene Therapy|July 2, 2025
miR-375 protects against acetaminophen-induced acute liver failure by orchestrating pharmacogene expressionYi Wang, Jinghua Liu, Sha Zhu, et al.Biorxiv : the Preprint Server for Biology|January 20, 2025
AAVone: A Cost-Effective, Single-Plasmid Solution for Efficient AAV Production with Reduced DNA ImpuritiesRongze Yang, Ngoc Tam Tran, Taylor Chen, et al.Molecular Therapy. Nucleic Acids|June 12, 2025
AAVone: A cost-effective, single-plasmid solution for efficient AAV production with reduced DNA impuritiesRongze Yang, Ngoc Tam Tran, Taylor Chen, et al.Pageof 1