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Cancer Research
|
August 24, 2016
The PARP Inhibitor AZD2461 Provides Insights into the Role of PARP3 Inhibition for Both Synthetic Lethality and Tolerability with Chemotherapy in Preclinical Models
Lenka Oplustil O'Connor, Stuart L Rulten, Aaron N Cranston, et al.
Molecular Cancer Therapeutics
|
May 12, 2012
Chemosensitization of cancer cells by KU-0060648, a dual inhibitor of DNA-PK and PI-3K
Joanne M Munck, Michael A Batey, Yan Zhao, et al.
Journal of Medicinal Chemistry
|
September 20, 2008
4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: a novel bioavailable inhibitor of poly(ADP-ribose) polymerase-1
Keith A Menear, Claire Adcock, Robert Boulter, et al.
Journal of Medicinal Chemistry
|
March 21, 2007
Pyranone, thiopyranone, and pyridone inhibitors of phosphatidylinositol 3-kinase related kinases. Structure-activity relationships for DNA-dependent protein kinase inhibition, and identification of the first potent and selective inhibitor of the ataxia telangiectasia mutated kinase
Jonathan J Hollick, Laurent J M Rigoreau, Celine Cano-Soumillac, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
July 13, 2026
The pharmacological profile of ART6043, a first-in-class clinical DNA polymerase theta polymerase domain inhibitor potentiating PARP inhibitor efficacy
Helen M R Robinson, Vera Grinkevich, Jayesh B Majithiya, et al.
Nature Communications
|
June 18, 2021
Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance
Diana Zatreanu, Helen M R Robinson, Omar Alkhatib, et al.
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Search research articles
Search
Showing results (21-30 of 26) with videos related to
Sort By:
Page
of 3
You have reached the last page of results.
This site can display upto 26 results.
Cancer Research
|
August 24, 2016
The PARP Inhibitor AZD2461 Provides Insights into the Role of PARP3 Inhibition for Both Synthetic Lethality and Tolerability with Chemotherapy in Preclinical Models
Lenka Oplustil O'Connor, Stuart L Rulten, Aaron N Cranston, et al.
Molecular Cancer Therapeutics
|
May 12, 2012
Chemosensitization of cancer cells by KU-0060648, a dual inhibitor of DNA-PK and PI-3K
Joanne M Munck, Michael A Batey, Yan Zhao, et al.
Journal of Medicinal Chemistry
|
September 20, 2008
4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: a novel bioavailable inhibitor of poly(ADP-ribose) polymerase-1
Keith A Menear, Claire Adcock, Robert Boulter, et al.
Journal of Medicinal Chemistry
|
March 21, 2007
Pyranone, thiopyranone, and pyridone inhibitors of phosphatidylinositol 3-kinase related kinases. Structure-activity relationships for DNA-dependent protein kinase inhibition, and identification of the first potent and selective inhibitor of the ataxia telangiectasia mutated kinase
Jonathan J Hollick, Laurent J M Rigoreau, Celine Cano-Soumillac, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
July 13, 2026
The pharmacological profile of ART6043, a first-in-class clinical DNA polymerase theta polymerase domain inhibitor potentiating PARP inhibitor efficacy
Helen M R Robinson, Vera Grinkevich, Jayesh B Majithiya, et al.
Nature Communications
|
June 18, 2021
Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance
Diana Zatreanu, Helen M R Robinson, Omar Alkhatib, et al.
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of 3