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Current Biology : CB|June 22, 2026
DNA synthesis: When amino acids act as a templateNicholas Chim, John C ChaputNucleic Acids Research|June 7, 2019
Crystal structures of a natural DNA polymerase that functions as an XNA reverse transcriptaseLynnette N Jackson, Nicholas Chim, Changhua Shi, et al.Quarterly Reviews of Biophysics|July 28, 2020
Engineering polymerases for applications in synthetic biologyAli Nikoomanzar, Nicholas Chim, Eric J Yik, et al.Nucleic Acids Research|October 11, 2021
Transliteration of synthetic genetic enzymesYajun Wang, Xiaolin Liu, Mouhamad Shehabat, et al.Nucleic Acids Research|September 20, 2022
Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acidMohammad Hajjar, Nicholas Chim, Chao Liu, et al.Elife|October 20, 2018
Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathwayNicholas Chim, Lynnette N Jackson, Anh M Trinh, et al.Nature Communications|November 29, 2017
Structural basis for TNA synthesis by an engineered TNA polymeraseNicholas Chim, Changhua Shi, Sujay P Sau, et al.Current Opinion in Chemical Biology|April 16, 2026
How custom polymerases are driving innovation in synthetic biologyMohammad Hajjar, Alex R Horton, Victoria A Maola, et al.Nature Communications|May 12, 2021
Following replicative DNA synthesis by time-resolved X-ray crystallographyNicholas Chim, Roman A Meza, Anh M Trinh, et al.Journal of the American Chemical Society|October 12, 2021
Synthesis and Polymerase Recognition of Threose Nucleic Acid Triphosphates Equipped with Diverse Chemical FunctionalitiesQingfeng Li, Victoria A Maola, Nicholas Chim, et al.Pageof 14