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Cancer Discovery|March 28, 2018
Identification of Pik3ca Mutation as a Genetic Driver of Prostate Cancer That Cooperates with Pten Loss to Accelerate Progression and Castration-Resistant GrowthHelen B Pearson, Jason Li, Valerie S Meniel, et al.
Proceedings of the National Academy of Sciences of the United States of America|May 19, 2010
PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor-positive breast cancerSherene Loi, Benjamin Haibe-Kains, Samira Majjaj, et al.
European Journal of Cancer (Oxford, England : 1990)|September 10, 2013
Synergistic inhibition of ovarian cancer cell growth by combining selective PI3K/mTOR and RAS/ERK pathway inhibitorsKaren E Sheppard, Carleen Cullinane, Katherine M Hannan, et al.
The Journal of Clinical Investigation|January 5, 2012
An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in miceKathryn M Kinross, Karen G Montgomery, Margarete Kleinschmidt, et al.
Communications Biology|June 5, 2025
Model systems and unique biological features of high and low-grade colorectal cancer (CRC) revealed by xenografting 84 human CRC cell linesIan Y Luk, Jennifer K Mooi, Dmitri Mouradov, et al.
Molecular Cell|August 11, 2023
PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostateTamara A M Chessa, Piotr Jung, Arqum Anwar, et al.
Nature Communications|November 25, 2017
Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doublingInma M Berenjeno, Roberto Piñeiro, Sandra D Castillo, et al.
Plos One|May 3, 2011
Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancersÅslaug Helland, Michael S Anglesio, Joshy George, et al.
Cell Death & Disease|October 19, 2021
Molecular and genomic characterisation of a panel of human anal cancer cell linesGlen R Guerra, Joseph C Kong, Rosemary M Millen, et al.
Carcinogenesis|February 25, 2016
Identification of the CIMP-like subtype and aberrant methylation of members of the chromosomal segregation and spindle assembly pathways in esophageal adenocarcinomaLutz Krause, Katia Nones, Kelly A Loffler, et al.
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