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Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology|April 8, 2025
Is Enhancer Function Driven by Protein-Protein Interactions? From Bacteria to LeukemiaNicholas T Crump, Thomas A MilneCellular and Molecular Life Sciences : CMLS|May 18, 2019
Why are so many MLL lysine methyltransferases required for normal mammalian development?Nicholas T Crump, Thomas A MilneProceedings of the National Academy of Sciences of the United States of America|April 27, 2011
Dynamic acetylation of all lysine-4 trimethylated histone H3 is evolutionarily conserved and mediated by p300/CBPNicholas T Crump, Catherine A Hazzalin, Erin M Bowers, et al.Journal of Molecular Biology|August 12, 2008
Reconstitution and analysis of the multienzyme Escherichia coli RNA degradosomeJonathan A R Worrall, Maria Górna, Nicholas T Crump, et al.Haematologica|February 12, 2026
EZH2 inhibition overcomes immunomodulatory drug resistance in multiple myeloma via a cereblon-dependent pathwayYigen Li, Amy Wilson, Yakinthi Chrisochoidou, et al.Experimental Hematology|June 4, 2026
Inhibition of MLLT1 limits growth of KMT2A::AFF1 leukaemias without killing healthy haematopoietic stem cellsShivani Rajhansa, Nicholas T Crump, Hwei Minn Khoo, et al.Nature Communications|January 12, 2021
BET inhibition disrupts transcription but retains enhancer-promoter contactNicholas T Crump, Erica Ballabio, Laura Godfrey, et al.Chembiochem : a European Journal of Chemical Biology|September 11, 2012
Live-cell studies of p300/CBP histone acetyltransferase activity and inhibitionBeverley M Dancy, Nicholas T Crump, Daniel J Peterson, et al.Genome Research|June 5, 2021
A KMT2A-AFF1 gene regulatory network highlights the role of core transcription factors and reveals the regulatory logic of key downstream target genesJoe R Harman, Ross Thorne, Max Jamilly, et al.Nature Communications|June 28, 2019
DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylationLaura Godfrey, Nicholas T Crump, Ross Thorne, et al.Pageof 3