Showing results (11-20 of 21) with videos related to

Sort By:
Pageof 3
Experimental Hematology & Oncology|September 22, 2023
Modelling acquired resistance to DOT1L inhibition exhibits the adaptive potential of KMT2A-rearranged acute lymphoblastic leukemiaPauline Schneider, Nicholas T Crump, Susan T C J M Arentsen-Peters, et al.
Oncogene|January 29, 2022
Potent, p53-independent induction of NOXA sensitizes MLL-rearranged B-cell acute lymphoblastic leukemia cells to venetoclaxKlaudyna Fidyt, Agata Pastorczak, Julia Cyran, et al.
Nature Communications|November 26, 2021
A human fetal liver-derived infant MLL-AF4 acute lymphoblastic leukemia model reveals a distinct fetal gene expression programSiobhan Rice, Thomas Jackson, Nicholas T Crump, et al.
Chemistry & Biology|June 11, 2010
Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitorErin M Bowers, Gai Yan, Chandrani Mukherjee, et al.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)|March 1, 2026
BCR::ABL1-Induced Enhancer Reprogramming Uncovers Hypersensitivity of Ph+B-ALL Cells to Enhancer-Targeting DrugsHan Leng Ng, Trudy Lee Glaser, Jintao Zhu, et al.
Leukemia|April 4, 2020
H3K79me2/3 controls enhancer-promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cellsLaura Godfrey, Nicholas T Crump, Sorcha O'Byrne, et al.
Basic Research in Cardiology|March 31, 2022
Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heartAlzbeta Hulikova, Kyung Chan Park, Aminah A Loonat, et al.
Cell Reports|May 12, 2021
Chromatin accessibility governs the differential response of cancer and T cells to arginine starvationNicholas T Crump, Andreas V Hadjinicolaou, Meng Xia, et al.
Nature Communications|August 25, 2023
MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemiaNicholas T Crump, Alastair L Smith, Laura Godfrey, et al.
Nature Cardiovascular Research|March 19, 2024
Disrupted propionate metabolism evokes transcriptional changes in the heart by increasing histone acetylation and propionylationKyung Chan Park, Nicholas T Crump, Niamh Louwman, et al.
Pageof 3