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Molecular Pharmacology|November 9, 2007
Functional characterization of bone morphogenetic protein binding sites and Smad1/5 activation in human vascular cellsPaul D Upton, Lu Long, Richard C Trembath, et al.
Global Cardiology Science & Practice|January 19, 2016
The promise of recombinant BMP ligands and other approaches targeting BMPR-II in the treatment of pulmonary arterial hypertensionMark L Ormiston, Paul D Upton, Wei Li, et al.
The Journal of Biological Chemistry|April 16, 2009
Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cellsPaul D Upton, Rachel J Davies, Richard C Trembath, et al.
Scientific Reports|September 19, 2019
A Bone Morphogenetic Protein (BMP)-derived Peptide Based on the Type I Receptor-binding Site Modifies Cell-type Dependent BMP SignallingZhen Tong, Jingxu Guo, Robert C Glen, et al.
American Journal of Physiology. Lung Cellular and Molecular Physiology|November 2, 2004
BMP4 inhibits proliferation and promotes myocyte differentiation of lung fibroblasts via Smad1 and JNK pathwaysTrina K Jeffery, Paul D Upton, Richard C Trembath, et al.
Human Molecular Genetics|May 22, 2024
Functional validation of EIF2AK4 (GCN2) missense variants associated with pulmonary arterial hypertensionGiulia Emanuelli, JiaYi Zhu, Wei Li, et al.
Pulmonary Pharmacology & Therapeutics|July 6, 2010
Intravenous epoprostenol versus high dose inhaled iloprost for long-term treatment of pulmonary hypertensionFrank Reichenberger, Ann Mainwood, Nicholas W Morrell, et al.
American Journal of Respiratory Cell and Molecular Biology|June 30, 2007
BMP4 induces HO-1 via a Smad-independent, p38MAPK-dependent pathway in pulmonary artery myocytesXudong Yang, Patty J Lee, Lu Long, et al.
Pulmonary Circulation|May 7, 2025
Activin-A Regulates Bone Morphogenetic Protein Signaling in Pulmonary Endothelial Cells Without Affecting Bone Morphogenetic Protein Type-II Receptor ExpressionBenjamin J Dunmore, Nobuhiro Kikuchi, Wei Li, et al.
The Journal of Biological Chemistry|September 20, 2014
Regulation of bone morphogenetic protein 9 (BMP9) by redox-dependent proteolysisZhenquan Wei, Richard M Salmon, Paul D Upton, et al.
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