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Molecular Cell|June 30, 2023
Base editor screens for in situ mutational scanning at scaleNicholas Z Lue, Brian B Liau
Current Protocols|December 21, 2022
CRISPR-Suppressor Scanning for Systematic Discovery of Drug-Resistance MutationsKevin C Ngan, Nicholas Z Lue, Ceejay Lee, et al.
Nature Chemical Biology|October 20, 2022
Base editor scanning charts the DNMT3A activity landscapeNicholas Z Lue, Emma M Garcia, Kevin C Ngan, et al.
Elife|September 3, 2025
DNA methylation insulates genic regions from CTCF loops near nuclear specklesShelby A Roseman, Allison P Siegenfeld, Ceejay Lee, et al.
ACS Chemical Biology|August 21, 2023
Base Editor Scanning Reveals Activating Mutations of DNMT3AEmma M Garcia, Nicholas Z Lue, Jessica K Liang, et al.
ACS Central Science|May 4, 2022
Profiling the Landscape of Drug Resistance Mutations in Neosubstrates to Molecular Glue DegradersPallavi M Gosavi, Kevin C Ngan, Megan J R Yeo, et al.
Nature Communications|July 20, 2022
Polycomb-lamina antagonism partitions heterochromatin at the nuclear peripheryAllison P Siegenfeld, Shelby A Roseman, Heejin Roh, et al.
Elife|February 10, 2023
Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machineryKevin Chun-Ho Ngan, Samuel M Hoenig, Hui Si Kwok, et al.
Cell Chemical Biology|May 20, 2017
Uncovering the Cellular Target of Agelastatin AYongho Park, Brian B Liau
Nature Chemical Biology|November 20, 2021
Discovering new biology with drug-resistance allelesAllyson M Freedy, Brian B Liau
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