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Drug Discovery Today|July 23, 2013
Generation and utility of genetically humanized mouse modelsNico Scheer, Mike Snaith, C Roland Wolf, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|July 13, 2013
Genetically humanized mouse models of drug metabolizing enzymes and transporters and their applicationsNico Scheer, C Roland Wolf
Drug Metabolism Reviews|November 24, 2012
Xenobiotic receptor humanized mice and their utilityNico Scheer, C Roland Wolf
Molecular Pharmacology|June 2, 2011
Quantitative prediction of human pregnane X receptor and cytochrome P450 3A4 mediated drug-drug interaction in a novel multiple humanized mouse lineMaki Hasegawa, Yury Kapelyukh, Harunobu Tahara, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 1, 2010
In vivo responses of the human and murine pregnane X receptor to dexamethasone in miceNico Scheer, Jillian Ross, Yury Kapelyukh, et al.
Drug Metabolism Reviews|June 12, 2009
Drug transporters: gatekeepers controlling access of xenobiotics to the cellular interiorLesley A Stanley, Brian C Horsburgh, Jillian Ross, et al.
Drug Metabolism Reviews|August 1, 2006
PXR and CAR: nuclear receptors which play a pivotal role in drug disposition and chemical toxicityLesley A Stanley, Brian C Horsburgh, Jillian Ross, et al.
Molecular Pharmacology|August 25, 2012
Generation and characterization of novel cytochrome P450 Cyp2c gene cluster knockout and CYP2C9 humanized mouse linesNico Scheer, Yury Kapelyukh, Lynsey Chatham, et al.
Molecular Pharmacology|February 7, 2015
Cytochrome b5 is a major determinant of human cytochrome P450 CYP2D6 and CYP3A4 activity in vivoColin J Henderson, Lesley A McLaughlin, Nico Scheer, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|August 25, 2012
Generation and characterization of a novel multidrug resistance protein 2 humanized mouse lineNico Scheer, Praveen Balimane, Michael D Hayward, et al.
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