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ACS Medicinal Chemistry Letters
|
August 27, 2016
CZ415, a Highly Selective mTOR Inhibitor Showing in Vivo Efficacy in a Collagen Induced Arthritis Model
Andrew D Cansfield, Tammy Ladduwahetty, Mihiro Sunose, et al.
The European Respiratory Journal
|
December 28, 2020
An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in <i>ex vivo</i> human precision-cut lung slices
Muzamil Majid Khan, Daniel Poeckel, Aliaksandr Halavatyi, et al.
Nature Methods
|
October 30, 2019
Biological plasticity rescues target activity in CRISPR knock outs
Arne H Smits, Frederik Ziebell, Gerard Joberty, et al.
ACS Medicinal Chemistry Letters
|
July 24, 2018
Discovery of a First-in-Class Gut-Restricted RET Kinase Inhibitor as a Clinical Candidate for the Treatment of IBS
Hilary Schenck Eidam, John Russell, Kaushik Raha, et al.
RSC Medicinal Chemistry
|
December 15, 2025
Discovery and optimization of pyrrolopyrimidines as highly potent, selective and brain-penetrant LRRK2 inhibitors
Jeffrey M Axten, Xiao Ding, Luigi Piero Stasi, et al.
Angewandte Chemie (International Ed. in English)
|
August 20, 2021
Discovery and Characterisation of Highly Cooperative FAK-Degrading PROTACs
Robert P Law, Joao Nunes, Chun-Wa Chung, et al.
Journal of Medicinal Chemistry
|
January 9, 2025
Phenotype-Led Identification of IL-10 Upregulators in Human CD4<sup>+</sup> T-cells and Elucidation of Their Pharmacology as Highly Selective CDK8/CDK19 Inhibitors
Simon Nicolle, Mike Barker, John Barrett, et al.
Cell
|
March 20, 2018
Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis
Mikhail M Savitski, Nico Zinn, Maria Faelth-Savitski, et al.
Communications Biology
|
March 22, 2020
Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2
Alina Mares, Afjal H Miah, Ian E D Smith, et al.
Molecular Cell
|
January 3, 2025
mRNA export factors store nascent transcripts within nuclear speckles as an adaptive response to transient global inhibition of transcription
Tobias D Williams, Ewa M Michalak, Kirstyn T Carey, et al.
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Search research articles
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Showing results (21-30 of 34) with videos related to
Sort By:
Page
of 4
ACS Medicinal Chemistry Letters
|
August 27, 2016
CZ415, a Highly Selective mTOR Inhibitor Showing in Vivo Efficacy in a Collagen Induced Arthritis Model
Andrew D Cansfield, Tammy Ladduwahetty, Mihiro Sunose, et al.
The European Respiratory Journal
|
December 28, 2020
An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in <i>ex vivo</i> human precision-cut lung slices
Muzamil Majid Khan, Daniel Poeckel, Aliaksandr Halavatyi, et al.
Nature Methods
|
October 30, 2019
Biological plasticity rescues target activity in CRISPR knock outs
Arne H Smits, Frederik Ziebell, Gerard Joberty, et al.
ACS Medicinal Chemistry Letters
|
July 24, 2018
Discovery of a First-in-Class Gut-Restricted RET Kinase Inhibitor as a Clinical Candidate for the Treatment of IBS
Hilary Schenck Eidam, John Russell, Kaushik Raha, et al.
RSC Medicinal Chemistry
|
December 15, 2025
Discovery and optimization of pyrrolopyrimidines as highly potent, selective and brain-penetrant LRRK2 inhibitors
Jeffrey M Axten, Xiao Ding, Luigi Piero Stasi, et al.
Angewandte Chemie (International Ed. in English)
|
August 20, 2021
Discovery and Characterisation of Highly Cooperative FAK-Degrading PROTACs
Robert P Law, Joao Nunes, Chun-Wa Chung, et al.
Journal of Medicinal Chemistry
|
January 9, 2025
Phenotype-Led Identification of IL-10 Upregulators in Human CD4<sup>+</sup> T-cells and Elucidation of Their Pharmacology as Highly Selective CDK8/CDK19 Inhibitors
Simon Nicolle, Mike Barker, John Barrett, et al.
Cell
|
March 20, 2018
Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis
Mikhail M Savitski, Nico Zinn, Maria Faelth-Savitski, et al.
Communications Biology
|
March 22, 2020
Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2
Alina Mares, Afjal H Miah, Ian E D Smith, et al.
Molecular Cell
|
January 3, 2025
mRNA export factors store nascent transcripts within nuclear speckles as an adaptive response to transient global inhibition of transcription
Tobias D Williams, Ewa M Michalak, Kirstyn T Carey, et al.
Page
of 4