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Journal of Pharmacokinetics and Pharmacodynamics|May 25, 2021
A latent variable approach to account for correlated inputs in global sensitivity analysisNicola Melillo, Adam S Darwich
Journal of Pharmacokinetics and Pharmacodynamics|December 16, 2018
Variance based global sensitivity analysis of physiologically based pharmacokinetic absorption models for BCS I-IV drugsNicola Melillo, Leon Aarons, Paolo Magni, et al.
Journal of Pharmacokinetics and Pharmacodynamics|March 25, 2019
Accounting for inter-correlation between enzyme abundance: a simulation study to assess implications on global sensitivity analysis within physiologically-based pharmacokineticsNicola Melillo, Adam S Darwich, Paolo Magni, et al.
Computer Methods and Programs in Biomedicine|April 11, 2023
mvLognCorrEst: an R package for sampling from multivariate lognormal distributions and estimating correlations from uncomplete correlation matrixAlessandro De Carlo, Elena Maria Tosca, Nicola Melillo, et al.
Clinical and Translational Science|February 12, 2020
Mechanistic Multiscale Pharmacokinetic Model for the Anticancer Drug 2',2'-difluorodeoxycytidine (Gemcitabine) in Pancreatic CancerMaria Garcia-Cremades, Nicola Melillo, Iñaki F Troconiz, et al.
Journal of Pharmacokinetics and Pharmacodynamics|July 9, 2023
A two-stages global sensitivity analysis by using the δ sensitivity index in presence of correlated inputs: application on a tumor growth inhibition model based on the dynamic energy budget theoryAlessandro De Carlo, Elena Maria Tosca, Nicola Melillo, et al.
The AAPS Journal|August 31, 2020
Inter-compound and Intra-compound Global Sensitivity Analysis of a Physiological Model for Pulmonary Absorption of Inhaled CompoundsNicola Melillo, Silvia Grandoni, Nicola Cesari, et al.
Frontiers in Pharmacology|October 30, 2023
Radius additivity score: a novel combination index for tumour growth inhibition in fixed-dose xenograft studiesNicola Melillo, Jake Dickinson, Lu Tan, et al.
Molecular Pharmaceutics|July 20, 2021
Physiologically Based Pharmacokinetic Modeling of Transporter-Mediated Hepatic Disposition of Imaging Biomarker Gadoxetate in RatsDaniel Scotcher, Nicola Melillo, Sirisha Tadimalla, et al.
Molecular Cancer Therapeutics|September 18, 2023
Novel Thienoduocarmycin-Trastuzumab ADC Demonstrates Strong Antitumor Efficacy with Favorable Safety Profile in Preclinical StudiesBarbara Valsasina, Paolo Orsini, Michele Caruso, et al.
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