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The AAPS Journal|October 17, 2023
Role of Modeling and Simulation in Preclinical and Clinical Long-Acting Injectable Drug DevelopmentMaxime Siemons, Bram Schroyen, Nicolas Darville, et al.
The AAPS Journal|December 1, 2022
Pharmacokinetics of Long-Acting Aqueous Nano-/Microsuspensions After Intramuscular Administration in Different Animal Species and Humans-a ReviewVy Thi Thanh Nguyen, Nicolas Darville, An Vermeulen
Toxicologic Pathology|November 4, 2017
Comparison of the Local Tolerability to 5 Long-acting Drug Nanosuspensions with Different Stabilizing Excipients, Following a Single Intramuscular Administration in the RatRonnie Chamanza, Nicolas Darville, Marjolein van Heerden, et al.
Molecular Pharmaceutics|January 5, 2021
Linking In Vitro Intrinsic Dissolution Rate and Thermodynamic Solubility with Pharmacokinetic Profiles of Bedaquiline Long-Acting Aqueous Microsuspensions in RatsVy Nguyen, Jan Bevernage, Nicolas Darville, et al.
Journal of Pharmaceutical Sciences|September 19, 2014
The use of supersaturation for the vaginal application of microbicides: a case study with dapivirineCarolien Grammen, Jakob Plum, Jeroen Van Den Brande, et al.
Journal of Pharmaceutical Sciences|May 22, 2014
Intramuscular administration of paliperidone palmitate extended-release injectable microsuspension induces a subclinical inflammatory reaction modulating the pharmacokinetics in ratsNicolas Darville, Marjolein van Heerden, An Vynckier, et al.
Toxicologic Pathology|December 25, 2015
Modeling the Time Course of the Tissue Responses to Intramuscular Long-acting Paliperidone Palmitate Nano-/Microcrystals and Polystyrene Microspheres in the RatNicolas Darville, Marjolein van Heerden, Tim Erkens, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society|April 13, 2016
The effect of macrophage and angiogenesis inhibition on the drug release and absorption from an intramuscular sustained-release paliperidone palmitate suspensionNicolas Darville, Marjolein van Heerden, Dirk Mariën, et al.
European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V|September 9, 2015
Multimodal non-linear optical imaging for the investigation of drug nano-/microcrystal-cell interactionsNicolas Darville, Jukka Saarinen, Antti Isomäki, et al.
ACS Medicinal Chemistry Letters|May 20, 2026
Discovery of 5‑Azaindole Inhibitors of O‑GlcNAcase for the Treatment of Alzheimer's Disease and Related TauopathiesJakob Bouton, Alexis Bretteville, Gary Tresadern, et al.
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