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Nicolas Moitessier

Showing results (71-80 of 82) with videos related to

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Journal of Medicinal Chemistry|December 1, 2015
3-Oxo-hexahydro-1H-isoindole-4-carboxylic Acid as a Drug Chiral Bicyclic Scaffold: Structure-Based Design and Preparation of Conformationally Constrained Covalent and Noncovalent Prolyl Oligopeptidase InhibitorsGaëlle Mariaule, Stéphane De Cesco, Francesco Airaghi, et al.
Protein Science : a Publication of the Protein Society|December 7, 2023
A naturally occurring G11S mutation in the 3C-like protease from the SARS-CoV-2 virus dramatically weakens the dimer interfaceGuanyu Wang, Felipe A Venegas, Andres M Rueda, et al.
Journal of Medicinal Chemistry|July 7, 2012
Virtual screening and computational optimization for the discovery of covalent prolyl oligopeptidase inhibitors with activity in human cellsStéphane De Cesco, Sébastien Deslandes, Eric Therrien, et al.
Journal of Medicinal Chemistry|February 15, 2022
Novel Aurora A and Protein Kinase C (α, β1, β2, and θ) Multitarget Inhibitors: Impact of Selenium Atoms on the Potency and SelectivityKrikor Bijian, Dominik Wernic, Anita K Nivedha, et al.
Chemmedchem|November 5, 2011
Platinum(II) phenanthroimidazoles for targeting telomeric G-quadruplexesKatherine J Castor, Johanna Mancini, Johans Fakhoury, et al.
Journal of Medicinal Chemistry|August 9, 2019
Integrated Synthetic, Biophysical, and Computational Investigations of Covalent Inhibitors of Prolyl Oligopeptidase and Fibroblast Activation Protein αJessica Plescia, Stéphane De Cesco, Mihai Burai Patrascu, et al.
Protein Science : a Publication of the Protein Society|August 25, 2025
Inhibitor-induced dimerization mediates lufotrelvir resistance in mutants of SARS-CoV-2 3C-like proteaseGuanyu Wang, Felipe Venegas, Andres Rueda, et al.
Journal of Medicinal Chemistry|August 5, 2005
Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimeticsStephen Hanessian, Hongying Yun, Yihua Hou, et al.
Journal of the American Chemical Society|September 23, 2017
4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene SilencingElise Malek-Adamian, Dale C Guenther, Shigeo Matsuda, et al.
European Journal of Medicinal Chemistry|January 7, 2022
Design, synthesis and in vitro evaluation of novel SARS-CoV-2 3CL<sup>pro</sup> covalent inhibitorsJulia K Stille, Jevgenijs Tjutrins, Guanyu Wang, et al.
Pageof 9

Showing results (71-80 of 82) with videos related to

Sort By:
Pageof 9
Journal of Medicinal Chemistry|December 1, 2015
3-Oxo-hexahydro-1H-isoindole-4-carboxylic Acid as a Drug Chiral Bicyclic Scaffold: Structure-Based Design and Preparation of Conformationally Constrained Covalent and Noncovalent Prolyl Oligopeptidase InhibitorsGaëlle Mariaule, Stéphane De Cesco, Francesco Airaghi, et al.
Protein Science : a Publication of the Protein Society|December 7, 2023
A naturally occurring G11S mutation in the 3C-like protease from the SARS-CoV-2 virus dramatically weakens the dimer interfaceGuanyu Wang, Felipe A Venegas, Andres M Rueda, et al.
Journal of Medicinal Chemistry|July 7, 2012
Virtual screening and computational optimization for the discovery of covalent prolyl oligopeptidase inhibitors with activity in human cellsStéphane De Cesco, Sébastien Deslandes, Eric Therrien, et al.
Journal of Medicinal Chemistry|February 15, 2022
Novel Aurora A and Protein Kinase C (α, β1, β2, and θ) Multitarget Inhibitors: Impact of Selenium Atoms on the Potency and SelectivityKrikor Bijian, Dominik Wernic, Anita K Nivedha, et al.
Chemmedchem|November 5, 2011
Platinum(II) phenanthroimidazoles for targeting telomeric G-quadruplexesKatherine J Castor, Johanna Mancini, Johans Fakhoury, et al.
Journal of Medicinal Chemistry|August 9, 2019
Integrated Synthetic, Biophysical, and Computational Investigations of Covalent Inhibitors of Prolyl Oligopeptidase and Fibroblast Activation Protein αJessica Plescia, Stéphane De Cesco, Mihai Burai Patrascu, et al.
Protein Science : a Publication of the Protein Society|August 25, 2025
Inhibitor-induced dimerization mediates lufotrelvir resistance in mutants of SARS-CoV-2 3C-like proteaseGuanyu Wang, Felipe Venegas, Andres Rueda, et al.
Journal of Medicinal Chemistry|August 5, 2005
Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimeticsStephen Hanessian, Hongying Yun, Yihua Hou, et al.
Journal of the American Chemical Society|September 23, 2017
4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene SilencingElise Malek-Adamian, Dale C Guenther, Shigeo Matsuda, et al.
European Journal of Medicinal Chemistry|January 7, 2022
Design, synthesis and in vitro evaluation of novel SARS-CoV-2 3CL<sup>pro</sup> covalent inhibitorsJulia K Stille, Jevgenijs Tjutrins, Guanyu Wang, et al.
Pageof 9