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Journal of Structural Biology: X
|
July 11, 2020
Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158
Yvonne Grobben, Joost C M Uitdehaag, Nicole Willemsen-Seegers, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
May 19, 2020
High-Throughput Fluorescence-Based Activity Assay for Arginase-1
Yvonne Grobben, Nicole Willemsen-Seegers, Joost C M Uitdehaag, et al.
Journal of Molecular Biology
|
January 4, 2017
Compound Selectivity and Target Residence Time of Kinase Inhibitors Studied with Surface Plasmon Resonance
Nicole Willemsen-Seegers, Joost C M Uitdehaag, Martine B W Prinsen, et al.
Angewandte Chemie (International Ed. in English)
|
April 12, 2017
Optimized Target Residence Time: Type I1/2 Inhibitors for p38α MAP Kinase with Improved Binding Kinetics through Direct Interaction with the R-Spine
Heike K Wentsch, Niklas M Walter, Mike Bührmann, et al.
Journal of Medicinal Chemistry
|
August 24, 2017
Design, Synthesis, and Biological Evaluation of Novel Type I<sup>1</sup>/<sub>2</sub> p38α MAP Kinase Inhibitors with Excellent Selectivity, High Potency, and Prolonged Target Residence Time by Interfering with the R-Spine
Niklas M Walter, Heike K Wentsch, Mike Bührmann, et al.
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|
March 13, 2021
Mapping Arginase Expression with <sup>18</sup>F-Fluorinated Late-Generation Arginase Inhibitors Derived from Quaternary α-Amino Acids
Gonçalo S Clemente, Inês F Antunes, Santosh Kurhade, et al.
Molecular Cancer Therapeutics
|
November 2, 2018
Combined Cellular and Biochemical Profiling to Identify Predictive Drug Response Biomarkers for Kinase Inhibitors Approved for Clinical Use between 2013 and 2017
Joost C M Uitdehaag, Jeffrey J Kooijman, Jeroen A D M de Roos, et al.
Oncotarget
|
April 19, 2017
Stable aneuploid tumors cells are more sensitive to TTK inhibition than chromosomally unstable cell lines
Marion A A Libouban, Jeroen A D M de Roos, Joost C M Uitdehaag, et al.
Journal of Molecular Biology
|
May 26, 2017
Target Residence Time-Guided Optimization on TTK Kinase Results in Inhibitors with Potent Anti-Proliferative Activity
Joost C M Uitdehaag, Jos de Man, Nicole Willemsen-Seegers, et al.
Molecular Cancer Therapeutics
|
September 3, 2016
Cell Panel Profiling Reveals Conserved Therapeutic Clusters and Differentiates the Mechanism of Action of Different PI3K/mTOR, Aurora Kinase and EZH2 Inhibitors
Joost C M Uitdehaag, Jeroen A D M de Roos, Martine B W Prinsen, et al.
Page
of 2
Search research articles
Search
Showing results (1-10 of 14) with videos related to
Sort By:
Page
of 2
Journal of Structural Biology: X
|
July 11, 2020
Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158
Yvonne Grobben, Joost C M Uitdehaag, Nicole Willemsen-Seegers, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
May 19, 2020
High-Throughput Fluorescence-Based Activity Assay for Arginase-1
Yvonne Grobben, Nicole Willemsen-Seegers, Joost C M Uitdehaag, et al.
Journal of Molecular Biology
|
January 4, 2017
Compound Selectivity and Target Residence Time of Kinase Inhibitors Studied with Surface Plasmon Resonance
Nicole Willemsen-Seegers, Joost C M Uitdehaag, Martine B W Prinsen, et al.
Angewandte Chemie (International Ed. in English)
|
April 12, 2017
Optimized Target Residence Time: Type I1/2 Inhibitors for p38α MAP Kinase with Improved Binding Kinetics through Direct Interaction with the R-Spine
Heike K Wentsch, Niklas M Walter, Mike Bührmann, et al.
Journal of Medicinal Chemistry
|
August 24, 2017
Design, Synthesis, and Biological Evaluation of Novel Type I<sup>1</sup>/<sub>2</sub> p38α MAP Kinase Inhibitors with Excellent Selectivity, High Potency, and Prolonged Target Residence Time by Interfering with the R-Spine
Niklas M Walter, Heike K Wentsch, Mike Bührmann, et al.
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|
March 13, 2021
Mapping Arginase Expression with <sup>18</sup>F-Fluorinated Late-Generation Arginase Inhibitors Derived from Quaternary α-Amino Acids
Gonçalo S Clemente, Inês F Antunes, Santosh Kurhade, et al.
Molecular Cancer Therapeutics
|
November 2, 2018
Combined Cellular and Biochemical Profiling to Identify Predictive Drug Response Biomarkers for Kinase Inhibitors Approved for Clinical Use between 2013 and 2017
Joost C M Uitdehaag, Jeffrey J Kooijman, Jeroen A D M de Roos, et al.
Oncotarget
|
April 19, 2017
Stable aneuploid tumors cells are more sensitive to TTK inhibition than chromosomally unstable cell lines
Marion A A Libouban, Jeroen A D M de Roos, Joost C M Uitdehaag, et al.
Journal of Molecular Biology
|
May 26, 2017
Target Residence Time-Guided Optimization on TTK Kinase Results in Inhibitors with Potent Anti-Proliferative Activity
Joost C M Uitdehaag, Jos de Man, Nicole Willemsen-Seegers, et al.
Molecular Cancer Therapeutics
|
September 3, 2016
Cell Panel Profiling Reveals Conserved Therapeutic Clusters and Differentiates the Mechanism of Action of Different PI3K/mTOR, Aurora Kinase and EZH2 Inhibitors
Joost C M Uitdehaag, Jeroen A D M de Roos, Martine B W Prinsen, et al.
Page
of 2