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Frontiers in Pharmacology|July 24, 2012
New and paradoxical roles of matrix metalloproteinases in the tumor microenvironmentAgnès Noël, Ana Gutiérrez-Fernández, Nor Eddine Sounni, et al.
The Journal of Biological Chemistry|March 26, 2008
A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptorThore Hillig, Lars H Engelholm, Signe Ingvarsen, et al.
Molecules (Basel, Switzerland)|January 25, 2025
A HER2 Specific Nanobody-Drug Conjugate: Site-Selective Bioconjugation and In Vitro Evaluation in Breast Cancer ModelsAnders H Hansen, Kasper I H Andersen, Li Xin, et al.
The Journal of Biological Chemistry|September 19, 2008
Antibody-mediated targeting of the urokinase-type plasminogen activator proteolytic function neutralizes fibrinolysis in vivoIda K Lund, Annika Jögi, Birgitte Rønø, et al.
Cancer Gene Therapy|September 19, 2024
BAG2, MAD2L1, and MDK are cancer-driver genes and candidate targets for novel therapies in malignant pleural mesotheliomaLuisa Bisceglia, Federica Morani, Lara Guerrieri, et al.
Plos One|August 14, 2013
Differential actions of the endocytic collagen receptor uPARAP/Endo180 and the collagenase MMP-2 in bone homeostasisDaniel H Madsen, Henrik J Jürgensen, Signe Ingvarsen, et al.
The Journal of Cell Biology|June 22, 2005
Intracellular collagen degradation mediated by uPARAP/Endo180 is a major pathway of extracellular matrix turnover during malignancyAlejandro C Curino, Lars H Engelholm, Susan S Yamada, et al.
Cell Reports|December 28, 2017
Tumor-Associated Macrophages Derived from Circulating Inflammatory Monocytes Degrade Collagen through Cellular UptakeDaniel Hargbøl Madsen, Henrik Jessen Jürgensen, Majken Storm Siersbæk, et al.
The Journal of Biological Chemistry|February 7, 2014
Complex determinants in specific members of the mannose receptor family govern collagen endocytosisHenrik J Jürgensen, Kristina Johansson, Daniel H Madsen, et al.
Science Advances|January 17, 2025
Targeting uPAR with an antibody-drug conjugate suppresses tumor growth and reshapes the immune landscape in pancreatic cancer modelsVirginia Metrangolo, Michaela Hansen Blomquist, Ananya Dutta, et al.
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