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Cancer Research Communications|December 10, 2025
Targeting uPARAP with an antibody-drug conjugate exhibits efficacy against mesothelioma and synergizes with cisplatinPınar Çakılkaya, Ida Marie Egeland Larsen, Qun Jiang, et al.
Scientific Reports|November 6, 2020
Tumor cell MT1-MMP is dispensable for osteosarcoma tumor growth, bone degradation and lung metastasisSigne Z Ingvarsen, Henrik Gårdsvoll, Sander van Putten, et al.
Molecular Cancer Therapeutics|July 16, 2025
The recycling collagen receptor uPARAP is a unique mediator of stromal drug delivery to carcinoma cellsKirstine S Nørregaard, Ida M E Larsen, Henrik J Jürgensen, et al.
The Journal of Cell Biology|April 2, 2003
uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesionLars H Engelholm, Karin List, Sarah Netzel-Arnett, et al.
Nature Communications|December 7, 2018
uPARAP/Endo180 receptor is a gatekeeper of VEGFR-2/VEGFR-3 heterodimerisation during pathological lymphangiogenesisTania Durré, Florent Morfoisse, Charlotte Erpicum, et al.
Oncotarget|June 3, 2017
The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancersChristoffer Fagernæs Nielsen, Sander Maarten van Putten, Ida Katrine Lund, et al.
The Journal of Cell Biology|September 11, 2013
M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathwayDaniel H Madsen, Daniel Leonard, Andrius Masedunskas, et al.
The Journal of Pathology|October 16, 2015
Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180Lars H Engelholm, Maria C Melander, Andreas Hald, et al.
The Journal of Cell Biology|January 27, 2026
uPA-mediated remodeling of CCL21 gradients regulates lymphatic migration of dendritic cellsVictor Collado-Diaz, Maria-Nefeli Christakopoulou, Philipp Schineis, et al.
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