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Cells|January 21, 2023
The Bronchoprotective Effects of Dual Pharmacology, Muscarinic Receptor Antagonist and β2 Adrenergic Receptor Agonist Navafenterol in Human Small AirwaysJoseph Antony Jude, Ian Dainty, Nikhil Karmacharya, et al.
Respiratory Research|April 12, 2019
Salicylic acid amplifies Carbachol-induced bronchoconstriction in human precision-cut lung slicesJoseph Jude, Danielle Botelho, Nikhil Karmacharya, et al.
American Journal of Physiology. Lung Cellular and Molecular Physiology|July 5, 2022
Obesity elicits a unique metabolomic signature in human airway smooth muscle cellsShengjie Xu, Nikhil Karmacharya, Gaoyuan Cao, et al.
Respiratory Research|December 4, 2025
Long-acting β2 agonist (LABA) with a long-acting muscarinic receptor antagonist (LAMA) promotes human airway smooth muscle (HASM) relaxation and circumvents β2 adrenergic receptor tachyphylaxisJoseph Jude, Nikhil Karmacharya, Rinzhin T Sherpa, et al.
American Journal of Respiratory Cell and Molecular Biology|October 13, 2022
Starving a Cell Promotes Airway Smooth Muscle Relaxation: Inhibition of Glycolysis Attenuates Excitation-Contraction CouplingShengjie Xu, Nikhil Karmacharya, Joanna Woo, et al.
Respiratory Research|December 1, 2020
FFAR1 activation attenuates histamine-induced myosin light chain phosphorylation and cortical tension development in human airway smooth muscle cellsShengjie Xu, Anthony Schwab, Nikhil Karmacharya, et al.
Respiratory Research|November 22, 2025
The differential effects of cAMP mobilizing agents on TGF-β-induced extracellular matrix in human lung-derived fibroblasts: insights into therapeutic targets for lung fibrosisSarah Orfanos, Brian T Deeney, Gaoyuan Cao, et al.
American Journal of Respiratory Cell and Molecular Biology|October 29, 2024
Volume-Regulated Anion Channel Complex Modulates Mechano-Electrical Signal Responses in Human Airway Smooth Muscle ShorteningJoanna Woo, Gaoyuan Cao, Nikhil Karmacharya, et al.
American Journal of Respiratory Cell and Molecular Biology|October 14, 2021
Inhibition of ABCC1 Decreases cAMP Egress and Promotes Human Airway Smooth Muscle Cell RelaxationGaoyuan Cao, Hong Lam, Joseph A Jude, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 24, 2020
The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTRJessie Huang, Hong Lam, Cynthia Koziol-White, et al.
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