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Nature|November 19, 2025
Hepatic zonation determines tumorigenic potential of mutant β-cateninAlexander Raven, Kathryn Gilroy, Hu Jin, et al.
Nature Communications|June 9, 2021
Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesisJoshua D G Leach, Nikola Vlahov, Petros Tsantoulis, et al.
Cancer Discovery|December 17, 2020
MNK Inhibition Sensitizes KRAS-Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC ExpressionJohn R P Knight, Constantinos Alexandrou, George L Skalka, et al.
Nature Genetics|January 8, 2021
The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancerArafath K Najumudeen, Fatih Ceteci, Sigrid K Fey, et al.
Nature|November 25, 2025
MAPK-driven epithelial cell plasticity drives colorectal cancer therapeutic resistanceMark White, Megan L Mills, Laura M Millett, et al.
Nature Metabolism|August 14, 2023
Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic targetJohan Vande Voorde, Rory T Steven, Arafath K Najumudeen, et al.
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