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Nature Communications|April 6, 2023
Automated optimisation of solubility and conformational stability of antibodies and proteinsAngelo Rosace, Anja Bennett, Marc Oeller, et al.Mabs|May 27, 2026
Prediction of antibody non-specificity using protein language models and biophysical parametersLaila I Sakhnini, Ludovica Beltrame, Simone Fulle, et al.Nature Reviews. Chemistry|April 28, 2023
Non-specificity as the sticky problem in therapeutic antibody developmentHannes Ausserwöger, Matthias M Schneider, Therese W Herling, et al.The Journal of Biological Chemistry|November 23, 2012
The neuroendocrine protein 7B2 suppresses the aggregation of neurodegenerative disease-related proteinsMichael Helwig, Akina Hoshino, Casey Berridge, et al.Biochimica Et Biophysica Acta|January 15, 2013
Off-pathway aggregation can inhibit fibrillation at high protein concentrationsTaru Deva, Nikolai Lorenzen, Brian S Vad, et al.Mabs|September 21, 2020
An accelerated surface-mediated stress assay of antibody instability for developability studiesMarie R G Kopp, Adriana-Michelle Wolf Pérez, Marta Virginia Zucca, et al.Biochemistry|September 14, 2014
High stability and cooperative unfolding of α-synuclein oligomersWojciech Paslawski, Maria Andreasen, Søren Bang Nielsen, et al.Molecular Pharmaceutics|January 20, 2023
AF4 and PEG Precipitation as Predictive Assays for Antibody Self-AssociationItzel Condado-Morales, Viktoria Sokolova, Per-Olof Wahlund, et al.Proceedings of the National Academy of Sciences of the United States of America|December 18, 2023
Nonspecificity fingerprints for clinical-stage antibodies in solutionTherese W Herling, Gaetano Invernizzi, Hannes Ausserwöger, et al.Proceedings of the National Academy of Sciences of the United States of America|July 27, 2016
The neural chaperone proSAAS blocks α-synuclein fibrillation and neurotoxicityTimothy S Jarvela, Hoa A Lam, Michael Helwig, et al.Pageof 4