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The EMBO Journal|April 16, 2002
A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctionsPhilippe Marambaud, Junichi Shioi, Geo Serban, et al.FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|May 20, 2015
Presenilin 1 is necessary for neuronal, but not glial, EGFR expression and neuroprotection via γ-secretase-independent transcriptional mechanismsJulien Bruban, Georgios Voloudakis, Qian Huang, et al.Journal of Alzheimer'S Disease : JAD|April 24, 2009
Leptin: a novel therapeutic strategy for Alzheimer's diseaseNikolaos Tezapsidis, Jane M Johnston, Mark A Smith, et al.Ageing Research Reviews|July 6, 2023
Passive Alzheimer's immunotherapy: A promising or uncertain option?Poul F Høilund-Carlsen, Mona-Elisabeth Revheim, Tommaso Costa, et al.Human Molecular Genetics|March 24, 2017
Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia lociJohn F Fullard, Claudia Giambartolomei, Mads E Hauberg, et al.Brain Communications|October 2, 2020
Presenilin1 familial Alzheimer disease mutants inactivate EFNB1- and BDNF-dependent neuroprotection against excitotoxicity by affecting neuroprotective complexes of N-methyl-d-aspartate receptorMd Al Rahim, Yonejung Yoon, Christina Dimovasili, et al.Neurobiology of Disease|June 25, 2002
Overexpression of wild type but not an FAD mutant presenilin-1 promotes neurogenesis in the hippocampus of adult micePaul H Wen, Xiang Shao, Zhiping Shao, et al.Molecular Psychiatry|June 17, 2020
PS1 FAD mutants decrease ephrinB2-regulated angiogenic functions, ischemia-induced brain neovascularization and neuronal survivalYoneJung Yoon, Georgios Voloudakis, Nathan Doran, et al.Chemical Communications (Cambridge, England)|February 5, 2020
Substrate interaction inhibits γ-secretase production of amyloid-β peptidesJing Zhao, Yuanyuan Xiao, Xinyue Liu, et al.Journal of Alzheimer'S Disease : JAD|June 19, 2023
The Anti-Amyloid Monoclonal Antibody Lecanemab: 16 Cautionary NotesKasper P Kepp, Stefano L Sensi, Kasper B Johnsen, et al.Pageof 6