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Scientific Reports|January 31, 2025
TRα1 mutant suppresses KLF9 to cause endometrial metaplasia with ectopic IL-33 expression leading to uterine fibrosis and infertilityElijah Edmondson, Takahito Kimura, Eunmi Hwang, et al.
Cell Reports|September 1, 2023
Irreversible cell cycle exit associated with senescence is mediated by constitutive MYC degradationMarwa M Afifi, Adrijana Crncec, James A Cornwell, et al.
Chembiochem : a European Journal of Chemical Biology|April 30, 2014
Charge density influences C1 domain ligand affinity and membrane interactionsJessica S Kelsey, Tamas Geczy, Nancy E Lewin, et al.
Journal of Medicinal Chemistry|April 22, 2009
Conformationally constrained analogues of diacylglycerol (DAG). 31. Modulation of the biological properties of diacylgycerol lactones (DAG-lactones) containing rigid-rod acyl groups separated from the core lactone by spacer units of different lengthsMaria J Comin, Gabriella Czifra, Noemi Kedei, et al.
Organic Letters|December 31, 2008
Substitution on the A-ring confers to bryopyran analogues the unique biological activity characteristic of bryostatins and distinct from that of the phorbol estersGary E Keck, Yam B Poudel, Dennie S Welch, et al.
Oncogene|May 24, 2011
RasGRP3, a Ras activator, contributes to signaling and the tumorigenic phenotype in human melanomaDazhi Yang, Juan Tao, Luowei Li, et al.
Plos One|August 31, 2013
RasGRPs are targets of the anti-cancer agent ingenol-3-angelateXiaohua Song, Ana Lopez-Campistrous, Lucy Sun, et al.
Cancers|February 25, 2023
SMAC Mimetics Synergistically Cooperate with HDAC Inhibitors Enhancing TNF-α Autocrine SignalingYusuke Shibuya, Kei Kudo, Kristen P Zeligs, et al.
The Journal of Biological Chemistry|March 30, 2016
Structural Basis for the Failure of the C1 Domain of Ras Guanine Nucleotide Releasing Protein 2 (RasGRP2) to Bind Phorbol Ester with High AffinityAgnes Czikora, Daniel J Lundberg, Adelle Abramovitz, et al.
Chembiochem : a European Journal of Chemical Biology|May 5, 2011
Some phorbol esters might partially resemble bryostatin 1 in their actions on LNCaP prostate cancer cells and U937 leukemia cellsNoemi Kedei, Emanuel Lubart, Nancy E Lewin, et al.
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