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Pharmacological Research|October 16, 2023
IUPHAR themed review: Opioid efficacy, bias, and selectivityNokomis Ramos-Gonzalez, Barnali Paul, Susruta MajumdarTrends in Pharmacological Sciences|January 18, 2025
Advances in the structural understanding of opioid allosteryNokomis Ramos-Gonzalez, Balazs R Varga, Susruta MajumdarBritish Journal of Pharmacology|May 24, 2021
The anomalous pharmacology of fentanylEamonn Kelly, Katy Sutcliffe, Damiana Cavallo, et al.British Journal of Pharmacology|April 3, 2023
Carfentanil is a β-arrestin-biased agonist at the μ opioid receptorNokomis Ramos-Gonzalez, Sam Groom, Katy J Sutcliffe, et al.Science Advances|March 25, 2026
Mechanistic insights into the therapeutic properties of delta opioid receptorSarah M Bernhard, Susovan Roy Chowdhury, Tsuyoshi Murata, et al.Nature Chemical Biology|January 8, 2025
Molecular mechanisms of inverse agonism via κ-opioid receptor-G protein complexesAaliyah S Tyson, Saif Khan, Zenia Motiwala, et al.Proceedings of the National Academy of Sciences of the United States of America|June 30, 2025
Total synthesis and biological activity of "carbamorphine": O-to-CH2 replacement in the E-ring of the morphine core structureSota Akiyama, Rohini S Ople, Alexander Kremsmair, et al.Nature Structural & Molecular Biology|June 22, 2026
Structural basis of opioid receptor activation by PCP and ketamineQianru Jiang, Jianming Han, Eve J Fine, et al.ACS Central Science|September 2, 2024
Signaling Modulation Mediated by Ligand Water Interactions with the Sodium Site at μORRohini S Ople, Nokomis Ramos-Gonzalez, Qiongyu Li, et al.Nature|March 5, 2025
A cryptic pocket in CB1 drives peripheral and functional selectivityVipin Ashok Rangari, Evan S O'Brien, Alexander S Powers, et al.Pageof 2