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Cell Reports|April 21, 2015
Astrocyte-derived TGF-β1 accelerates disease progression in ALS mice by interfering with the neuroprotective functions of microglia and T cellsFumito Endo, Okiru Komine, Noriko Fujimori-Tonou, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 15, 2023
Mitochondria-associated membrane collapse impairs TBK1-mediated proteostatic stress response in ALSSeiji Watanabe, Yuri Murata, Yasuyoshi Oka, et al.
Iscience|February 6, 2024
Genetic background variation impacts microglial heterogeneity and disease progression in amyotrophic lateral sclerosis model miceOkiru Komine, Syuhei Ohnuma, Kunihiko Hinohara, et al.
Molecular Brain|November 13, 2020
Touchscreen-based location discrimination and paired associate learning tasks detect cognitive impairment at an early stage in an App knock-in mouse model of Alzheimer's diseaseMd Ali Bin Saifullah, Okiru Komine, Yutao Dong, et al.
Molecular Brain|August 30, 2014
SIRT1 overexpression ameliorates a mouse model of SOD1-linked amyotrophic lateral sclerosis via HSF1/HSP70i chaperone systemSeiji Watanabe, Natsumi Ageta-Ishihara, Shinji Nagatsu, et al.
Acta Neuropathologica Communications|February 20, 2016
Neuregulin 1 confers neuroprotection in SOD1-linked amyotrophic lateral sclerosis mice via restoration of C-boutons of spinal motor neuronsJurate Lasiene, Okiru Komine, Noriko Fujimori-Tonou, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|September 24, 2005
Differential roles of glial and neuronal glutamate transporters in Purkinje cell synapsesYukihiro Takayasu, Masae Iino, Wataru Kakegawa, et al.
Acta Neuropathologica Communications|July 27, 2019
Mice deficient in the C-terminal domain of TAR DNA-binding protein 43 develop age-dependent motor dysfunction associated with impaired Notch1-Akt signaling pathwayKohei Nishino, Seiji Watanabe, Jin Shijie, et al.
Cell Death & Disease|November 25, 2024
Microglial cannabinoid receptor type II stimulation improves cognitive impairment and neuroinflammation in Alzheimer's disease mice by controlling astrocyte activationAkira Sobue, Okiru Komine, Fumito Endo, et al.
The Journal of Experimental Medicine|July 2, 2003
The Runx1 transcription factor inhibits the differentiation of naive CD4+ T cells into the Th2 lineage by repressing GATA3 expressionOkiru Komine, Keitaro Hayashi, Waka Natsume, et al.
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