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Drug Metabolism and Disposition: the Biological Fate of Chemicals|October 18, 2012
Evaluation and prediction of potential drug-drug interactions of linagliptin using in vitro cell culture methodsNaoki Ishiguro, Hidetada Shimizu, Wataru Kishimoto, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|November 12, 2013
In vitro predictability of drug-drug interaction likelihood of P-glycoprotein-mediated efflux of dabigatran etexilate based on [I]2/IC50 thresholdWataru Kishimoto, Naoki Ishiguro, Eva Ludwig-Schwellinger, et al.Journal of Agricultural and Food Chemistry|April 14, 2005
Development of a radioimmunoassay for the quantitative determination of 8-prenylnaringenin in biological matricesOlaf Schaefer, Rolf Bohlmann, Wolf-Dieter Schleuning, et al.The Journal of Biological Chemistry|February 9, 2002
Dissociation time from DNA determines transcriptional function in a STAT1 linker mutantEdward Yang, Melissa A Henriksen, Olaf Schaefer, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|November 12, 2013
Impact of endogenous esterase activity on in vitro p-glycoprotein profiling of dabigatran etexilate in Caco-2 monolayersNaoki Ishiguro, Wataru Kishimoto, Astrid Volz, et al.The Journal of Steroid Biochemistry and Molecular Biology|September 13, 2005
Tissue specificity of 8-prenylnaringenin: protection from ovariectomy induced bone loss with minimal trophic effects on the uterusMichael Hümpel, Päivi Isaksson, Olaf Schaefer, et al.Journal of Pharmaceutical Sciences|May 6, 2011
Reliability and robustness of simultaneous absolute quantification of drug transporters, cytochrome P450 enzymes, and Udp-glucuronosyltransferases in human liver tissue by multiplexed MRM/selected reaction monitoring mode tandem mass spectrometry with nano-liquid chromatographyAtsushi Sakamoto, Takehisa Matsumaru, Naoki Ishiguro, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|October 8, 2011
Absolute quantification and differential expression of drug transporters, cytochrome P450 enzymes, and UDP-glucuronosyltransferases in cultured primary human hepatocytesOlaf Schaefer, Sumio Ohtsuki, Hirotaka Kawakami, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|October 14, 2011
Simultaneous absolute protein quantification of transporters, cytochromes P450, and UDP-glucuronosyltransferases as a novel approach for the characterization of individual human liver: comparison with mRNA levels and activitiesSumio Ohtsuki, Olaf Schaefer, Hirotaka Kawakami, et al.Proceedings of the National Academy of Sciences of the United States of America|March 9, 2005
Implications of an antiparallel dimeric structure of nonphosphorylated STAT1 for the activation-inactivation cycleMinghao Zhong, Melissa A Henriksen, Kenji Takeuchi, et al.Pageof 2