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Investigational New Drugs|May 4, 2004
Efficacy of novel P-glycoprotein inhibitors to increase the oral uptake of paclitaxel in miceHeleen A Bardelmeijer, Mariët Ouwehand, Jos H Beijnen, et al.Investigational New Drugs|May 2, 2008
The effect of P-gp (Mdr1a/1b), BCRP (Bcrp1) and P-gp/BCRP inhibitors on the in vivo absorption, distribution, metabolism and excretion of imatinibRoos L Oostendorp, Tessa Buckle, Jos H Beijnen, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 21, 2008
Extensive metabolism and hepatic accumulation of gemcitabine after multiple oral and intravenous administration in miceStephan A Veltkamp, Dick Pluim, Olaf van Tellingen, et al.Cancer Research|March 22, 2003
Mouse breast cancer resistance protein (Bcrp1/Abcg2) mediates etoposide resistance and transport, but etoposide oral availability is limited primarily by P-glycoproteinJohn D Allen, Sonja C Van Dort, Marije Buitelaar, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|November 3, 2007
P-glycoprotein and breast cancer resistance protein: two dominant transporters working together in limiting the brain penetration of topotecanNienke A de Vries, Jin Zhao, Emily Kroon, et al.Current Clinical Pharmacology|January 20, 2009
Evaluation of human plasma protein binding of trabectedin (Yondelis, ET-743)Jan Handrick Beumer, L Lopez-Lazaro, Jan H M Schellens, et al.Investigational New Drugs|August 1, 2014
"Effect of the drug transporters ABCB1, ABCC2, and ABCG2 on the disposition and brain accumulation of the taxane analog BMS-275,183"Serena Marchetti, Dick Pluim, Jos H Beijnen, et al.Molecular Pharmaceutics|October 18, 2015
Preclinical Mouse Models To Study Human OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions in VivoSelvi Durmus, Gloria Lozano-Mena, Anita van Esch, et al.CNS Oncology|July 24, 2014
Targeting core (mutated) pathways of high-grade gliomas: challenges of intrinsic resistance and drug effluxFan Lin, Mark C de Gooijer, Diana Hanekamp, et al.International Journal of Cancer|December 18, 2007
Magnetic resonance imaging-based detection of glial brain tumors in mice after antiangiogenic treatmentAn Claes, Giulio Gambarota, Bob Hamans, et al.Pageof 14