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Scientific Reports|November 4, 2025
Heterogeneity in an adeno-associated virus transfection-based production process limits the production efficiencyBrian Ladd, Sofia Tunmats, Torbjörn Gräslund, et al.
Biotechnology Progress|October 10, 2013
A high-yielding CHO transient system: coexpression of genes encoding EBNA-1 and GS enhances transient protein expressionOlalekan Daramola, Jessica Stevenson, Greg Dean, et al.
Biotechnology Journal|June 10, 2025
Intensification of rAAV Production Based on HEK293 Cell Transient TransfectionYe Zhang, Emil Sundäng Peters, Olalekan Daramola, et al.
Biotechnology Progress|December 7, 2013
Predicting the expression of recombinant monoclonal antibodies in Chinese hamster ovary cells based on sequence features of the CDR3 domainLeon P Pybus, David C James, Greg Dean, et al.
Biotechnology Journal|May 16, 2017
Polysome profiling of mAb producing CHO cell lines links translational control of cell proliferation and recombinant mRNA loading onto ribosomes with global and recombinant protein synthesisCharlotte L Godfrey, Emma J Mead, Olalekan Daramola, et al.
Biotechnology Progress|October 18, 2011
Cell line specific control of polyethylenimine-mediated transient transfection optimized with "Design of experiments" methodologyBen C Thompson, Camille R J Segarra, Olivia L Mozley, et al.
Biotechnology and Bioengineering|October 2, 2013
Model-directed engineering of "difficult-to-express" monoclonal antibody production by Chinese hamster ovary cellsLeon P Pybus, Greg Dean, Nathan R West, et al.
Biotechnology Progress|April 28, 2023
CHO synthetic promoters improve expression and product quality of biotherapeutic proteinsSi Nga Sou, Claire L Harris, Rebecca Williams, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|June 1, 2024
In vivo mRNA expression of a multi-mechanistic mAb combination protects against Staphylococcus aureus infectionChristine Tkaczyk, Michael Newton, Mun Mun Patnaik, et al.
Mabs|March 24, 2022
Suitability of transiently expressed antibodies for clinical studies: product quality consistency at different production scalesSara Rodriguez-Conde, Sophie Inman, Viv Lindo, et al.
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