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Science (New York, N.Y.)|July 24, 2025
Molecular glues that facilitate RAS binding to PI3Kα promote glucose uptake without insulinKoji Terayama, Shinji Furuzono, Nicole Fer, et al.
Analytical Chemistry|March 18, 2024
A Top-Down Proteomic Assay to Evaluate KRAS4B-Compound EngagementRobert A D'Ippolito, Dana Rabara, Maria Abreu Blanco, et al.
Science Signaling|September 28, 2017
Evaluation of the selectivity and sensitivity of isoform- and mutation-specific RAS antibodiesAndrew M Waters, Irem Ozkan-Dagliyan, Angelina V Vaseva, et al.
Plos One|February 8, 2014
Antitumor activity and induction of TP53-dependent apoptosis toward ovarian clear cell adenocarcinoma by the dual PI3K/mTOR inhibitor DS-7423Tomoko Kashiyama, Katsutoshi Oda, Yuji Ikeda, et al.
Cancer Discovery|December 16, 2014
Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction mapMaria M Martins, Alicia Y Zhou, Alexandra Corella, et al.
Nature Medicine|November 28, 2018
Aurora kinase A drives the evolution of resistance to third-generation EGFR inhibitors in lung cancerKhyati N Shah, Roma Bhatt, Julia Rotow, et al.
Cell Reports Methods|October 21, 2021
Targeted mass spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP Kinase, and AKT signalingJeffrey R Whiteaker, Kanika Sharma, Melissa A Hoffman, et al.
American Journal of Medical Genetics. Part A|January 9, 2020
Advancing RAS/RASopathy therapies: An NCI-sponsored intramural and extramural collaboration for the study of RASopathiesAndrea M Gross, Megan Frone, Karen W Gripp, et al.
Nature Communications|January 12, 2024
Functional interactions between neurofibromatosis tumor suppressors underlie Schwann cell tumor de-differentiation and treatment resistanceHarish N Vasudevan, Emily Payne, Cyrille L Delley, et al.
Biorxiv : the Preprint Server for Biology|May 7, 2026
Dual inhibition of GTP-bound (ON) and GDP-bound (OFF) KRAS G12C suppresses PI3Kα and leads to potent tumor inhibitionKatherine Parker, Samar Ghorbanpoor, Wafa Malik, et al.
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