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Chemical Biology & Drug Design|October 5, 2023
Targeted modification of furan-2-carboxaldehydes into Michael acceptor analogs yielded long-acting hemoglobin modulators with dual antisickling activitiesAbdelsattar M Omar, Osheiza Abdulmalik, Khalid M El-Say, et al.
The Journal of Clinical Investigation|July 4, 2007
An erythroid chaperone that facilitates folding of alpha-globin subunits for hemoglobin synthesisXiang Yu, Yi Kong, Louis C Dore, et al.
Biorxiv : the Preprint Server for Biology|April 27, 2026
Dissecting polycomb complexes for enhanced fetal hemoglobin productionPaul J Kaminski, Kristen Min, Elizabeth A Traxler, et al.
Biochemistry|November 20, 2015
Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Prodrugs as Drug Candidates for the Treatment of Ischemic Disorders: Insights into NO-Releasing Prodrug Biotransformation and Hemoglobin-NO BiochemistryGuoyan G Xu, Tanvi M Deshpande, Mohini S Ghatge, et al.
Blood|May 29, 2026
Dissecting polycomb complexes for enhanced fetal hemoglobin productionPaul Kaminski, Kristen Min, Elizabeth A Traxler, et al.
Pharmaceuticals (Basel, Switzerland)|June 27, 2025
Michael Acceptor Compounds as Hemoglobin Oxygen Affinity Modulators for Reversing Sickling of Red Blood CellsKhadijah A Mohammad, Asala H Naghi, Mohini S Ghatge, et al.
Blood|April 17, 2020
The HRI-regulated transcription factor ATF4 activates BCL11A transcription to silence fetal hemoglobin expressionPeng Huang, Scott A Peslak, Xianjiang Lan, et al.
Biomolecules|May 28, 2022
Design, Synthesis, and Antisickling Investigation of a Nitric Oxide-Releasing Prodrug of 5HMF for the Treatment of Sickle Cell DiseaseRana T Alhashimi, Mohini S Ghatge, Akua K Donkor, et al.
Scientific Reports|November 21, 2020
VZHE-039, a novel antisickling agent that prevents erythrocyte sickling under both hypoxic and anoxic conditionsOsheiza Abdulmalik, Piyusha P Pagare, Boshi Huang, et al.
Acta Crystallographica. Section D, Biological Crystallography|November 22, 2011
Crystallographic analysis of human hemoglobin elucidates the structural basis of the potent and dual antisickling activity of pyridyl derivatives of vanillinOsheiza Abdulmalik, Mohini S Ghatge, Faik N Musayev, et al.
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