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Cell Metabolism|February 2, 2022
Erythrocyte transglutaminase-2 combats hypoxia and chronic kidney disease by promoting oxygen delivery and carnitine homeostasisPing Xu, Changhan Chen, Yujin Zhang, et al.
ACS Chemical Biology|July 26, 2014
Identification of a small molecule that increases hemoglobin oxygen affinity and reduces SS erythrocyte sicklingAkito Nakagawa, Francine E Lui, Dina Wassaf, et al.
Journal of Thrombosis and Haemostasis : JTH|July 7, 2021
Pathologically stiff erythrocytes impede contraction of blood clotsValerie Tutwiler, Rustem I Litvinov, Anna Protopopova, et al.
Molecular Pharmaceutics|September 1, 2017
Design, Synthesis, and Biological Evaluation of Ester and Ether Derivatives of Antisickling Agent 5-HMF for the Treatment of Sickle Cell DiseaseGuoyan G Xu, Piyusha P Pagare, Mohini S Ghatge, et al.
Blood Advances|September 21, 2020
HRI depletion cooperates with pharmacologic inducers to elevate fetal hemoglobin and reduce sickle cell formationScott A Peslak, Eugene Khandros, Peng Huang, et al.
Pharmaceutics|August 28, 2021
Improving the Solubility and Oral Bioavailability of a Novel Aromatic Aldehyde Antisickling Agent (PP10) for the Treatment of Sickle Cell DiseaseTarek A Ahmed, Khalid M El-Say, Fathy I Abd-Allah, et al.
Fetal Diagnosis and Therapy|February 1, 2019
Erythropoietin Prevents Anemia and Transfusions in Extremely Premature Lambs Supported by an EXTrauterine Environment for Neonatal Development (EXTEND)Ali Y Mejaddam, Matthew A Hornick, Patrick E McGovern, et al.
Molecular Pharmaceutics|April 11, 2018
A Triazole Disulfide Compound Increases the Affinity of Hemoglobin for Oxygen and Reduces the Sickling of Human Sickle CellsAkito Nakagawa, Michele Ferrari, Grigorij Schleifer, et al.
Blood Advances|January 30, 2024
Modeling primitive and definitive erythropoiesis with induced pluripotent stem cellsGiulia Pavani, Joshua G Klein, Catriana C Nations, et al.
Blood Advances|May 27, 2022
Identification and characterization of RBM12 as a novel regulator of fetal hemoglobin expressionAoi Wakabayashi, Maryanne Kihiu, Malini Sharma, et al.
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